On label and off label drug use in the treatment of female infertility

Capsule:
Female infertility is often treated with both off-label medications and those approved by the US Food and Drug Administration. This review describes commonly used drugs for this indication.

Authors:
Rebecca S. Usadi, M.D., Kathryn S. Merriam, B.A.

Volume 103, Issue 3, Pages 583-594

Abstract:

Female infertility affects millions of couples worldwide and is estimated to account for one-third of all cases of infertility. The purpose of this article is to review the uses of both off-label treatments and those approved by the US Food and Drug Administration for female infertility, by examining the mechanism of action, the side-effect profile, fetal anomaly risks, and contraindications for the various drugs.

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