Sildenafil stimulates human trophoblast invasion through nitric oxide and guanosine 3 5 cyclic monophosphate signaling

Monday, June 1, 2015
A specific phosphodiesterase type 5 inhibitor, sildenafil, promotes extravillous differentiation and increases invasiveness of first-trimester trophoblast cells through the nitricoxide–driven cGMPpathway.

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Leukemia inhibitory factor increases the invasiveness of trophoblastic cells through integrated increase in the expression of adhesion molecules and pappalysin 1 with a concomitant decrease…

Monday, February 4, 2013
Microarray data revealed altered expression of several novel invasion-associated molecules in leukemia inhibitory factor (LIF)-treated HTR-8/SVneo cells, wherein silencing of pappalysin 1 reduced LIF-mediated invasion.

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