Transplantation of frozen thawed ovarian tissue demonstrate high reproductive performance and the need to revise restrictive criteria

Wednesday, April 20, 2016

Authors:
Dror Meirow, M.D.correspondenceemail, Hila Ra’anani, M.D., Moran Shapira, M.D., Masha Brenghausen, Ph.D., Chaim Sanaz Derech, B.Sc., Sarit Aviel-Ronen, M.D., Ph.D., Ninette Amerilgio, M.D., Eyal Schiff, M.D., Raoul Orvieto, M.D., Jehoshua Dor, M.D.…

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One uterus bridging three generations First live birth after mother to daughter uterus transplantation

Friday, April 1, 2016

Authors:
Mats Brännström, M.D., Ph.D., Hans Bokström, M.D., Ph.D., Pernilla Dahm-Kähler, M.D., Ph.D., Cesar Diaz-Garcia, M.D., Ph.D., Jana Ekberg, M.D., Ph.D., Anders Enskog, M.D., Ph.D., Henrik Hagberg, M.D., Ph.D., Liza Johannesson, M.D., Ph.D., Niclas Kvarnström, M.D., Johan Mölne, M.D., Ph.D., Michael Olausson, M.D., Ph.D., Jan I.…

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Experimental methods to preserve male fertility and treat male factor infertility

Monday, February 1, 2016
This article describes experimental stem cell and gene therapies that might be used to treat male factor infertility.

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Uterus transplantation trial Psychological evaluation of recipients and partners during the post transplantation year

Tuesday, September 29, 2015
Nine women with uterine factor infertility and their partners underwent psychological evaluations, by questionnaires, before and after uterus transplantation. The participants were psychologically stable throughout the 1-year observation time.

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Pregnancies and live births after 20 transplantations of cryopreserved ovarian tissue in a single center

Friday, January 30, 2015
Preserving fertility by cryopreserving ovarian tissue is a successful and safe clinical option that can be considered for selected cancer patients.

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Uterus retrieval process from brain dead donors

Wednesday, July 30, 2014
We describe the feasibility of human uterus retrieval from brain dead donors. Uterus retrieval could be part of a reproducible multiorgan procurement procedure. Uterus donation seems readily accepted.

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Ethics of uterus transplantation with live donors

Wednesday, June 25, 2014
Before launching live donor liver transplantation in Chicago, the preparations included thorough ethical discussion, which was subsequently published in The New England Journal of Medicine.

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The first clinical uterus transplantation trial A six-month report

Wednesday, April 30, 2014
The 6-month results of the first clinical trial of uterus transplantation are presented. The feasibility of live donor uterus transplantation with a low-dose immunosuppressive protocol is demonstrated.

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Testicular cell transplantation into the human testes

Monday, September 30, 2013
Human cadaver testes were infused with 99mtechnetium-labeled green fluorescent protein-positive testicular cells. This study shows that injecting a cell suspension in seminiferous tubules is possible, though further optimization is required.

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Uterine rejection after allogeneic uterus transplantation in the rat is effectively suppressed by tacrolimus

Friday, March 1, 2013
In a rat model of allogeneic uterus transplantation, the immunosuppressant tacrolimus effectively prevented uterine rejection, and expression patterns of inflammation-/implantation-related proteins of the uteri were similar to those of controls.

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Uterus transplantation

Monday, February 4, 2013
Reflections on "Preliminary results of the first human uterus transplantation from a multiorgan donor" by Ozkan et al.

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In search of an efficient injection technique for future clinical application of spermatogonial stem cell transplantation Infusion of contrast dyes in isolated cadaveric human testes

Thursday, November 29, 2012
Different injection methods and sites were used to evaluate the feasibility of human testes injection. A single ultrasound-guided injection of 800 mL in the rete testis was efficacious.

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Live birth after transplantation of frozen-thawed ovarian tissue after bilateral oophorectomy for benign disease

Thursday, June 7, 2012
Ovarian function was restored and pregnancy achieved in a woman who had previously undergone bilateral oophorectomy for benign disease and in whom frozen-thawed ovarian cortex was subsequently autotransplanted.

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Evaluation of the ovarian reserve in women transplanted with frozen and thawed ovarian cortical tissue

Thursday, May 31, 2012
The follicle pool in transplanted frozen/thawed ovarian tissue is low compared with normal ovaries, and reduced follicular selection may explain these women’s poor reproductive outcomes in assisted reproduction.

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Uterus transplantation: animal research and human possibilities

Wednesday, May 30, 2012
We describe uterus transplantation research conducted in the animalmodel and explore its introduction in the human model.

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Orthotopic grafting of cryopreserved prepubertal testicular tissue: in search of a simple yet effective cryopreservation protocol

Friday, May 4, 2012
Solid-surface vitrification resulted in success rates similar to conventional uncontrolled slow freezing inpreserving the integrity and function of prepubertalmouse testicular tissue.

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