Sonographic markers of ovarian morphology but not hirsutism indices predict serum total testosterone in women with regular menstrual cycles

Sunday, May 1, 2016
We discuss how total testosterone levels were predicted by sonographic markers of ovarian morphology, not hirsutism scores; and how the predictive value of ovarian morphology for total testosterone differed by menstrual cycle status.

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Antimüllerian hormone Correlation with age and androgenic and metabolic factors in women from birth to postmenopause

Monday, February 1, 2016
Antimullerian hormone, which elevates from birth to 18 years of age and declines thereafter, is positively correlated with androgen levels in adolescent and reproductive-aged women.

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Cross sectional study of factors influencing sex hormone binding globulin concentrations in normally cycling premenopausal women

Monday, November 30, 2015
In normally cycling premenopausal women, SHBG concentrations, independently from other parameters, are negatively associated with bioavailable T and positively associated with adiponectin.

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Infertility as a proxy of general male health Results of a cross sectional survey

Monday, June 29, 2015
Men with decreased general health status have lower sperm concentration, lower testosterone levels, and higher follicle-stimulating hormone values. Poorer health status appears associated with a malfunctioning male reproductive system.

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Impairment of male reproductive function after sleep deprivation

Wednesday, April 29, 2015
Sleep loss can promote marked changes in the male reproductive system in rodents, affecting especially the spermatic function by means of NO pathway modulation.

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Biomarkers of exposure to molybdenum and other metals in relation to testosterone among men from the United States National Health and Nutrition Examination Survey 2011 2012

Monday, December 29, 2014
Molybdenum and several other metals were associated with altered testosterone in men, which may have important implications as altered testosterone has been linked to many adverse health effects.

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Ovarian morphology assessed by magnetic resonance imaging in women with and without polycystic ovary syndrome and associations to anti Müllerian hormone free testosterone and glucose disposal rate

Sunday, June 1, 2014
Magnetic resonance imaging yielded higher antral follicle counts (AFC) than previously reported. AFC, antimullerian hormone, and free testosterone discriminated with high accuracy between women with polycystic ovary syndrome and controls.

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Specificity and predictive value of circulating testosterone assessed by tandem mass spectrometry for the diagnosis of polycystic ovary syndrome by the National Institutes of Health 1990 criteria

Monday, March 31, 2014
Extraction chromatography–radioimmunoassay and liquid chromatography–tandem mass spectrometry measurements of testosterone have similar performance for differentiating polycystic ovary syndrome from controls; different cutoff values should be considered depending on the setting (e.g., clinical vs. general populations).

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Testosterone use in the male infertility population prescribing patterns and effects on semen and hormonal parameters

Tuesday, December 31, 2013
In Canada, testosterone is not commonly used by men presenting for fertility investigation (1.3%). Testosterone cessation generally resulted in an increase in sperm counts. A subset of men remained azoospermic.

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Managing female sexual dysfunction

Monday, September 30, 2013
Female sexual dysfunctions (FSDs) may present as major emotional disturbances adversely affecting family and workplace. Although highly effective treatments exist, physicians frequently do not ask women about FSD.

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Sperm retrieval in adolescents with Klinefelter syndrome

Monday, September 30, 2013
Reflections on "Successful testicular sperm retrieval in adolescents with Klinefelter syndrome treated with at least 1 year of topical testosterone and aromatase inhibitor" by Mehta et al.

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Successful testicular sperm retrieval in adolescents with Klinefelter syndrome treated with at least 1 year of topical testosterone and aromatase inhibitor

Monday, September 30, 2013
Sperm retrieval and cryopreservation is possible in adolescents with Klinefelter syndrome who are actively being treated with topical testosterone replacement therapy.

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Scientific overview of hormone treatment used for rejuvenation

Friday, May 31, 2013
There is little evidence to support hormone replacement in older males with normal levels. Men with vitamin D deficiency and hypogonadal males, in some cases, benefit from hormone replacement.

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Determinants of testosterone recovery after bariatric surgery is it only a matter of reduction of body mass index

Friday, May 31, 2013
Body mass index correlation with sex hormones is exponential for testosterone and power for sex hormone–binding globulin (SHBG). Bariatric surgery improves all parameters with a higher than expected (for corresponding weight loss) increase of total testosterone and SHBG.

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The Significance of insulin-like factor 3 as a marker of intratesticular testosterone

Wednesday, January 2, 2013
Reflections on "Serum insulin-like factor 3 is highly correlated with intratesticular testosterone in normal men with acute, experimental gonadotropin deficiency stimulated with low-dose human chorionic gonadotropin: a randomized, controlled trial" by Roth et al.

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Role of decreased androgens in the ovarian response to stimulation in older women

Wednesday, January 2, 2013
As decreased ovarian testosterone production with age may compromise ovarian stimulation, we review maneuvers aimed at increasing ovarian testosterone and the likely potentiating effects of insulin-like growth factor I.

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Aromatase inhibitors for male infertility

Thursday, November 29, 2012
Aromatase inhibitors increase serum testosterone levels and can improve sperm production for infertile men with low serum testosterone and increased testosterone/estradiol ratios.

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Peritubular cells may modulate Leydig cell mediated testosterone production through a nonclassic pathway

Thursday, November 1, 2012
Peritubular cell secreted factor(s) may modulate T production by Leydig cells in a nonclassic mode, independent of StAR gene expression even in a gonadotropin-deficient environment.

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Acute Effects of Blood transfusion on Pituitary Gonadal Axis and Sperm Parameters in Adolescents and Young Menwith Thalassemia Major: A Pilot Study

Thursday, June 21, 2012
This study suggests that in thalassemic men, blood transfusion is associated with significant acute enhancement of sperm parameters and increased concentrations of serum T, LH, FSH, and IGF-1.

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Early pregnancy testosterone after ovarian stimulation and pregnancy outcome

Thursday, May 31, 2012
Ovarian stimulation before conception is associated with significant elevations in first-trimester testosterone. Further studies are needed to evaluate the effect of early pregnancy testosterone on outcomes.

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Effects of transdermal testosterone on natriuretic peptide levels in women: a randomized placebo-controlled pilot study

Thursday, May 31, 2012
This randomized placebo-controlled study demonstrated that low-dose testosterone administration decreases natriuretic peptide levels in women.

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