Sphingosine 1 phosphate suppresses cyclophosphamide induced follicle apoptosis in human fetal ovarian xenografts in nude mice

Tuesday, May 27, 2014
Antiapoptotic drug sphingosine-1-phosphate suppresses follicular depletion associated with chemotherapeutic agent cyclophosphamide treatment in human fetal ovarian xenografts, potentially providing a new option to prevent infertility associated with cancer treatments.

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Sphingosine pathway deregulation in endometriotic tissues

Thursday, May 10, 2012
Expression of sphingosine-1-phosphate catabolic enzymes and receptors is altered in endometriosis. These modifications enhance the sphingosine-1-phosphate axis, promoting survival and angiogenesis. This may contribute to the establishment and development of endometriosis.

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