Experimental methods to preserve male fertility and treat male factor infertility

Monday, February 1, 2016
This article describes experimental stem cell and gene therapies that might be used to treat male factor infertility.

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Cryopreservation of testicular tissue before long term testicular cell culture does not alter in vitro cell dynamics

Thursday, October 29, 2015
Cryopreservation of testicular tissue before culture does not influence the cell composition in longterm testicular cell cultures.

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Granulocyte colony stimulating factor prevents loss of spermatogenesis after sterilizing busulfan chemotherapy

Monday, December 29, 2014
Spermatogenesis can be destroyed by alkylating chemotherapies. In this study, spermatogenesis and undifferentiated spermatogonia in mice treated with busulfan were protected by treatment with granulocyte colony-stimulating factor.

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Enrichment of spermatogonial stem cells from long term cultured human testicular cells

Wednesday, July 30, 2014
Sorting long-term cultured human testicular cells for ITGA6 is an efficient strategy for enrichment of spermatogonial stem cells (SSC) and important for further characterization before clinical application of SSC autotransplantation.

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Optimizing cryopreservation of human spermatogonial stem cells Comparing the effectiveness of testicular tissue and single cell suspension cryopreservation

Monday, July 28, 2014
Optimal adult human SSC recovery is achieved with testicular cell suspension cryopreservation, whereas similar fetal SSC recovery was achieved with both tissue and single cell suspension cryopreservation.

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Haploid Sperm-Like Cells Created From Human Stem Cells – Sept 2012 Author Interview video

Sunday, September 16, 2012

September 2012 Featured Author Interview  – Drs.

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Spermatogonial stem cell preservation in Klinefelter boys: to bank or not to bank, that’s the question

Friday, June 8, 2012
To date, retrieval of spermatogonial cells in prepubertal boys with Klinefelter syndrome should be viewed as experimental and patients and their parents must be counseled accordingly.

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Presence of spermatogonia in 47,XXY men with no spermatozoa recovered after testicular sperm extraction

Thursday, May 24, 2012
Although their testes showed severe fibrosis and hyalinization, spermatogonia were observed in 4 of 22 Klinefelter syndrome patients with no sperm recovered after TESE.

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