Involvement of the inflammasome in abnormal semen quality of men with spinal cord injury

Wednesday, January 2, 2013
This study provides the first evidence that inflammasome proteins are present in human 24 semen, and suggests that the inflammatory innate immune response contributes to 25 abnormal semen quality in SCI men.

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Recommendations for gamete and embryo donation A committee opinion

Wednesday, January 2, 2013
This document provides the latest recommendations for evaluation of potential sperm, oocyte, and embryo donors.

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Variance in total levels of phospholipase C zeta PLCζ in human sperm may limit the applicability of quantitative immunofluorescent analysis as a diagnostic indicator of oocyte activation capability

Wednesday, January 2, 2013
Examination of total levels and localisation patterns of PLCζ in control and patient sperm. Sperm from control and OAD males exhibited significant variance in total levels and localization patterns of PLCζ protein.

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Smoking and infertility A committee opinion

Thursday, November 29, 2012
Smoking interferes with fertility of both males and females and can decrease the effectiveness of assisted reproductive technologies.

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Refining the measurement of sperm DNA fragmentation

Thursday, November 1, 2012
Reflections on "Oxidative DNA damage in human sperm can be detected by Raman microspectroscopy" by Sanchez et al.

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Sperm or No Sperm That Is the Question Finding the Elusive Spermatozoa

Thursday, September 27, 2012
Reflections on "Supersensitive fluorescent semen analysis: validation on azoospermic and oligozoospermic samples"

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Autocrine regulation of human sperm motility by the met-enkephalin opioid peptide

Friday, June 8, 2012
A novel role of the opioid system in the regulation of sperm function is demonstrated that shows that both exogenous and endogenous met-enkephalin can modulate sperm motility.

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Characterization of two heterozygous mutations of the oocyte activation factor phospholipase C zeta (PLCζ) from an infertile male by use of minisequencing of individual sperm and expression in somatic cells

Thursday, June 7, 2012
Investigating contributory factors to infertility in a man with two phospholipase C zeta (PLCz) mutations found loss-of-activity mutations in PLCz potentially resulting in a slower rate of mutant protein transcription.

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Full in vitro fertilization laboratory mechanization: toward robotic assisted reproduction?

Wednesday, May 30, 2012
Technologies related to automation, such as nonsubjective sperm selection, oocyte fertilization, and embryo culture and monitoring, are available, and this means that sample preparation, chemical or biologic reactions, and data collection could be integrated.

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Human spermatozoal RNAs

Thursday, May 24, 2012
A focused review is presented of the scientific literature pertaining to spermatozoal RNA.

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Recurrent implantation failure: gamete and embryo factors

Thursday, May 10, 2012
Recurrent implantation failure in IVF may be partially attributed to oocyte, sperm, and embryonic factors. Possible etiologies are reviewed and discussed, and recent advances in oocyte and embryo selection are evaluated along with current recommended management strategies.

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