Vascular endothelial growth factor pathway in endometriosis Genetic variants and plasma biomarkers

Friday, April 1, 2016
Our study showed that, in Caucasian women, genetic variants in the PLGF rs2268613 gene influences PLGF plasma levels. Plasma levels of VEGF were elevated in endometriosis patients compared with controls.

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Platelet specific collagen receptor glycoprotein VI gene variants affect recurrent pregnancy loss

Tuesday, July 1, 2014
This study observed increased risk for fetal losses with variants of platelet-specific collagen receptor glycoprotein VI. In silico analysis revealed the influence of glycoprotein VI in biologic pathways, collagen binding, and gene-gene interactions.

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Family based analysis of adiponectin gene polymorphisms in Chinese Han polycystic ovary syndrome

Wednesday, April 30, 2014
Transmission disequilibrium test analysis confirms that single-nucleotide polymorphism rs1501299 in ADIPOQ is significantly associated with risk of polycystic ovary syndrome in the Chinese population.

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rs189037 a functional variant in ATM gene promoter is associated with idiopathic nonobstructive azoospermia

Wednesday, November 27, 2013
Our case–control study, involving 229 idiopathic nonobstructive azoospermia (INOA) patients and 236 fertile male controls, indicates that rs189037(G>A) in ATM gene increases INOA risk, possibly through affecting ATM expression.

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Markedly elevated soluble E cadherin in plasma of patient with pelvic inflammatory disease

Monday, February 4, 2013
The level of plasma soluble E-cadherin was elevated in patients with pelvic inflammatory disease as compared with that in normal controls and in the same patients after they received treatment.

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Platelet aggregation abnormalities in patients with fetal losses The GP6 gene polymorphism

Thursday, November 1, 2012
This work evaluates the GP6 gene polymorphism in 27 patients with sticky platelet syndrome and fetal loss and in 42 healthy control subjects. Higher occurrence of two haplotypes in the patients shows that GP6 gene polymorphism may be associated with platelet hyperaggregability.

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Follicle-stimulating hormone receptor gene polymorphisms are not associated with ovarian reserve markers

Wednesday, May 23, 2012
This study evaluated the association between FSH receptor gene variants and current markers of ovarian reserve. No associations of FSH receptor genotypes with markers of ovarian reserve were detected.

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