MiOXSYS A novel method of measuring oxidation reduction potential in semen and seminal plasma

Monday, May 16, 2016

Authors:
Ashok Agarwal, Ph.D., H.C.L.D., Rakesh Sharma, Ph.D., Shubhadeep Roychoudhury, Ph.D., Stefan Du Plessis, Ph.D., Edmund Sabanegh, M.D.…

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Role of spermatozoa in the etiology of miscarriage

Tuesday, December 29, 2015

Author:
Richard Bronson, M.D.…

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Ability of Escherichia coli to produce hemolysis leads to a greater pathogenic effect on human sperm

Wednesday, April 29, 2015
Hemolytic Escherichia coli demonstrated a strain-dependent effect, altering all sperm variables studied, in contrast to nonhemolytic strains, which differentially impair sperm function.

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Benzoapyrene disrupts mouse preimplantation embryo development

Friday, February 27, 2015
Benzo(a)pyrene disrupts mouse preimplantation embryo development by increasing reactive oxygen species level, inducing genomic and telomeric DNA damage and cell apoptosis, and reducing inner cell mass ratio.

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Male infertility testing Reactive oxygen species and antioxidant capacity

Tuesday, November 25, 2014
Elevated reactive oxygen species (ROS) levels have been associated with abnormal semen parameters and male infertility. The impact ofROSon fertilization rates and pregnancy remains controversial.

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Reactive oxygen species in human semen Validation and qualification of a chemiluminescence assay

Tuesday, November 25, 2014
Reactive oxygen species can be measured accurately and reliably with the use of a simple luminol- based chemiluminescence assay. This test can be incorporated into routine testing of human semen for male infertility.

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Peroxynitrite affects the cumulus cell defense of metaphase II mouse oocytes leading to disruption of the spindle structure in vitro

Wednesday, July 31, 2013
Peroxynitrite generated in inflammatory states disrupts the cumulus oocyte complex and the spindle apparatus by dispersing and compromising the viability of cumulus cells, which may lead to infertility.

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Interaction between oviductal epithelial cells and spermatozoa underlies a systems biology approach to treating infertility

Thursday, March 28, 2013
Reflections on "Cell membrane proteins from oviductal epithelial cell line protect human spermatozoa from oxidative damage" by Chiu et al.

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Two dimensional differential in gel electrophoresis based proteomics of male gametes in relation to oxidative stress

Thursday, March 28, 2013
Proteomic analysis shows that differences in protein expression in spermatozoa producing higher levels of ROS may play a role in the pathophysiology of male infertility.

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Metformin decreases serum 8 hydroxy 2 deoxyguanosine levels in polycystic ovary syndrome

Monday, February 4, 2013
A double-blind, randomized, placebo-controlled trial on the effects of metformin on serum levels of 8-hydroxy-20-deoxyguanosine (8-OHdG) in women with polycystic ovary syndrome showed levels were statistically significantly reduced versus placebo.

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Superoxide dismutase content in sperm correlates with motility recovery after thawing of cryopreserved human spermatozoa

Thursday, May 24, 2012
The SOD content in mature sperm is a good predictor of post-thaw motility recovery of cryopreserved human spermatozoa.

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