Transcription factor SOHLH1 potentially associated with primary ovarian insufficiency

Friday, January 30, 2015
We identified 10 novel heterozygous variants in Chinese and Serbian partial ovarian insufficiency (POI) patients that point to SOHLH1 as a new POI candidate gene.

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Novel variants in the SOHLH2 gene are implicated in human premature ovarian failure

Monday, March 31, 2014
In large cohorts of Chinese and Serbian women with nonsyndromic premature ovarian failure, 11 novel heterozygous variants were identified in SOHLH2, with several predicted to be deleterious.

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Association of five common polymorphisms in the plasminogen activator inhibitor 1 gene with primary ovarian insufficiency

Thursday, February 20, 2014
PAI-1 9785GA+AA, 844A/9785A, 4G/9785A, and 9785A/11053Gmay contribute to prevalence of primary ovarian insufficiency (POI) in Korean women.

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NR5A1 SF1 gene variants in a group of 26 young women with XX primary ovarian insufficiency

Monday, February 4, 2013
In a primary ovarian insufficiency group, we identified one mutation and a frequent variant of the NR5A1/SF-1 gene. This work confirms the important role of steroidogenic factor 1 in ovarian function.

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Tumor necrosis factor alpha promoter polymorphisms are associated with idiopathic primary ovarian insufficiency in Korean women

Thursday, November 1, 2012
Tumor necrosis factor-a gene mutations may be responsible for the genetic susceptibility of Korean women to idiopathic primary ovarian insufficiency.

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Limited contribution of NR5A1 (SF-1) mutations in women with primary ovarian insufficiency (POI)

Friday, June 1, 2012
The prevalence of NR5A1 mutations in a large cohort of well-phenotyped women with secondary amenorrhea and diagnosed with POI was only 1.4%, which is substantially lower than previously reported.

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