Monday, June 29, 2015
We found that ADAMTS19 and BMPR2 mutations might be related to premature ovarian failure (POF) pathogenesis. We proposed that heterozygous LHCGR mutations might contribute, with variants in further POF genes, toward premature menopause.
Monday, March 31, 2014
In large cohorts of Chinese and Serbian women with nonsyndromic premature ovarian failure, 11 novel heterozygous variants were identified in SOHLH2, with several predicted to be deleterious.
Thursday, November 1, 2012
Gonadotropin-releasing hormone agonist cotreatment in conjunction with conditioning chemotherapy before stem cell transplantation may significantly decrease gonadotoxicity and premature ovarian failure in lymphoma but not in leukemia patients.
Thursday, September 27, 2012
Hypothesizing that a combination of polymorphic variants of major endocrine constituents of the menstrual cycle determines ovarian reserve, only the ESR1-PvuII polymorphism was found to be a potential candidate for early prediction of premature ovarian aging in female infertility.
Friday, May 11, 2012
This study revealed that both epistasis between singlenucleotide polymorphisms of HSD17B4 and TG and an HSD17B4 haplotype were significantly associated with premature ovarian failure.