Follicle stimulating hormone receptor polymorphism affects the outcome of ovulation induction in normogonadotropic World Health Organization class 2 anovulatory subfertility

Monday, March 30, 2015

Capsule:
An FSH receptor polymorphism (rs6166) affects the outcome of ovulation induction in normogonadotropic anovulatory subfertility.…

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Follow up to genome wide linkage and admixture mapping studies implicates components of the extracellular matrix in susceptibility to and size of uterine fibroids

Friday, January 30, 2015
Follow-up genetic association mapping implicates variant members of the collagen gene family in the development of uterine fibroids and suggests a defective extracellular matrix as a potential mechanism of pathogenesis.

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Association of CDKN2B AS and WNT4 genetic polymorphisms in Korean patients with endometriosis

Monday, July 14, 2014
This study demonstrated that the rs10965235 single-nucleotide polymorphism in the CDKN2B-AS gene and the rs16826658 single-nucleotide polymorphism near the WNT4 gene were significantly associated with endometriosis in a Korean population.

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Genetic variation of the E cadherin gene is associated with primary infertility in patients with ovarian endometriosis

Thursday, July 3, 2014
The study showed that genetic variants on the E-cadherin gene may be a potential molecular marker for the development of primary infertility in northern Chinese women with ovarian endometriosis.

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Interleukin 1β 511T C genetic variant contributes to recurrent pregnancy loss risk and peripheral natural killer cell proportion

Wednesday, June 25, 2014
IL-1b -511CC genotype was associated with increased recurrent pregnancy loss risk and peripheral natural killer cell proportion.

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Association of five common polymorphisms in the plasminogen activator inhibitor 1 gene with primary ovarian insufficiency

Thursday, February 20, 2014
PAI-1 9785GA+AA, 844A/9785A, 4G/9785A, and 9785A/11053Gmay contribute to prevalence of primary ovarian insufficiency (POI) in Korean women.

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Association of aberrant expression of sex determining gene fibroblast growth factor 9 with Sertoli cell only syndrome

Wednesday, November 27, 2013
Testicular fibroblast growth factor 9 (FGF9) is expressed in adult Leydig cells, and its expression is significantly decreased in patients with Sertoli cell–only syndrome. A promoter polymorphism of FGF9 contributes to its aberrant expression.

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A common gene variant in STK11 is associated with metabolic risk markers and diabetes during gestation

Friday, August 30, 2013
In pregnant women, the G allele for the rs8111699 variant in STK11 is associated with a more favorable metabolic phenotype and may protect against the development of gestational diabetes mellitus, particularly in heavier women.

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Mitochondrial displacement loop alterations are associated with endometriosis

Friday, May 31, 2013
Mitochondrial displacement (D-) loop alterations may constitute an inheritable risk factor for endometriosis. The analysis of D-loop alterations might help to identify patients at high risk for disease outcome.

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Genetic polymorphisms of serotonin transporter and receptor 1A could influence success during embryo implantation and maintenance of pregnancy

Friday, May 31, 2013
Exploratory genetic analysis of functional polymorphisms 5-HTTLPR and rs6295 reveals clinical implications during early pregnancy loss events in recipients undergoing IVF treatments using donated oocytes.

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Association of methionine synthase and thymidylate synthase genetic polymorphisms with idiopathic recurrent pregnancy loss

Tuesday, April 30, 2013
The MTR 2756AA and MTR 2756A–TS 6bp allele combination may contribute to prevalence of recurrent pregnancy loss (RPL) in Korean women.

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Dopamine receptor D2 genotype 3438 is associated with moderate severe endometriosis in infertile women in Brazil

Thursday, March 28, 2013
The frequency of the dopamine receptor D2 polymorphism 2 was increased in subjects with peritoneal moderate/severe endometriosis.

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Association of kinase insert domain containing receptor KDR gene polymorphisms with idiopathic recurrent spontaneous abortion in Korean women

Friday, March 1, 2013
The kinase insert domain-containing receptor 604T/C polymorphism is associated with recurrent spontaneous abortion (RSA) in Korean women, whereas the 1719A/T polymorphism that is associated with RSA in Taiwanese Han women is not associated with RSA in Korean women.

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Cytokine gene polymorphisms in northern Indian women with recurrent miscarriages

Monday, February 4, 2013
This study highlights the risk involving various genotypes and alleles of the interleukin (IL) 4 (C590T), IL-6 (G174C), IL-10 (1082A/G and 819C/T), and interferon-g (+874 A/T) polymorphism with recurrent miscarriage.

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G-protein β3 Subunit Gene 825C T Polymorphism and its Association with the Presence Severity and Duration of Vasculogenic Erectile Dysfunction

Wednesday, January 2, 2013
The CT genotype of GNB3 gene was more prevalent in patients with erectile dysfunction. The interaction between the T allele and erectile dysfunction was significant (P¼.004).

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Tumor necrosis factor alpha promoter polymorphisms are associated with idiopathic primary ovarian insufficiency in Korean women

Thursday, November 1, 2012
Tumor necrosis factor-a gene mutations may be responsible for the genetic susceptibility of Korean women to idiopathic primary ovarian insufficiency.

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The CC allele of the PvuII polymorphic variant in intron 1 of the α estrogen receptor gene is significantly more prevalent among infertile women at risk of premature ovarian aging

Thursday, September 27, 2012
Hypothesizing that a combination of polymorphic variants of major endocrine constituents of the menstrual cycle determines ovarian reserve, only the ESR1-PvuII polymorphism was found to be a potential candidate for early prediction of premature ovarian aging in female infertility.

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Epistasis between the HSD17B4 and TG polymorphisms is associated with premature ovarian failure

Friday, May 11, 2012
This study revealed that both epistasis between singlenucleotide polymorphisms of HSD17B4 and TG and an HSD17B4 haplotype were significantly associated with premature ovarian failure.

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Genetic association study of polymorphisms FOXP3 and FCRL3 in women with endometriosis

Friday, May 4, 2012
It has been suggested an immunologic mechanism is involved in the development of endometriosis. In a genetic association study, we demonstrated a cumulative effect of FOXP3 and FCRL3 polymorphisms in endometriosis.

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