Animal Models of Polycystic Ovary Syndrome: A Focused Review of Rodent Models in Relationship to Clinical Phenotypes and Cardiometabolic Risk

Thursday, June 7, 2012
This is a review of current rodent models used to investigate PCOS, including steroid-induced, pre- and postnatal, and genetic spontaneous models, in relationship to cardiometabolic risk factors, and the potential use of these models in understanding the etiology of cardiovascular disease in PCOS.

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Ultrasonographic measurement of the femoral cartilage thickness in patients with polycystic ovary syndrome

Monday, June 4, 2012
Patients with polycystic ovary syndrome seem to have thicker femoral cartilage than normal healthy women, but the increase does not correlate with the patients’ clinical parameters.

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Improvement of hyperandrogenism and hyperinsulinemia during pregnancy in women with polycystic ovary syndrome: possible effect in the ovarian follicular mass of their daughters

Monday, June 4, 2012
Lowering of androgens and insulin during pregnancy in mothers with polycystic ovary syndrome reduces anti-Mullerian hormone levels in their daughters, which might reflect a decrease in their follicular mass.

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Consensus on women’s health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group

Thursday, May 31, 2012
The third polycystic ovary syndrome (PCOS) consensus report summarizes current knowledge and identifies knowledge gaps regarding various women’s health aspects of PCOS.

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Should all women with PCOS be treated for insulin resistance?

Thursday, May 31, 2012
Insulin resistance of variable severity is commonly present in women with PCOS. Arguments and rationale are presented for treating all or only selected women with insulin sensitizing drugs.

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Do women with PCOS have a unique predisposition to obesity?

Thursday, May 31, 2012
Women with PCOS are often obese. There is debate in the literature regarding whether women are obese because of their PCOS status, or if those who become obese are more predisposed to PCOS.

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Does PCOS have developmental origins?

Thursday, May 31, 2012
The pros and cons of the proposition that PCOS has developmental origins are laid out based on the best available evidence.

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PCOS: key issues and remaining questions

Thursday, May 31, 2012
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women and yet remains enigmatic.

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Cross-sectional analysis of the effects of age on the hormonal, metabolic, and ultrasonographic features and the prevalence of the different phenotypes of polycystic ovary syndrome

Thursday, May 31, 2012
In women with PCOS, hyperandrogenemia appears to diminish during reproductive life whereas insulin resistance persists. This progressive worsening of insulin resistance is primarily driven by the increase in obesity.

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The risk of gestational diabetes mellitus among Mexican women with a history of infertility and polycystic ovary syndrome

Thursday, May 31, 2012
Pregnant Mexican women with a history of infertility and PCOS are at increased risk for developing GDM. This risk should be considered starting early in the second trimester for a timely intervention and to improve the maternal–fetal prognosis.

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Metabolic manifestations of polycystic ovary syndrome in nonobese adolescents: retinol-binding protein 4 and ectopic fat deposition

Friday, May 11, 2012
Adolescents with PCOS had higher intrahepatic lipid content and a statistical trend for higher retinol-binding protein 4 (RBP4) levels than controls. There may be an independent relationship between RBP4 and triglycerides.

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