Specificity and predictive value of circulating testosterone assessed by tandem mass spectrometry for the diagnosis of polycystic ovary syndrome by the National Institutes of Health 1990 criteria

Monday, March 31, 2014
Extraction chromatography–radioimmunoassay and liquid chromatography–tandem mass spectrometry measurements of testosterone have similar performance for differentiating polycystic ovary syndrome from controls; different cutoff values should be considered depending on the setting (e.g., clinical vs. general populations).

Read More

Progression to impaired glucose tolerance or type 2 diabetes mellitus in polycystic ovary syndrome A controlled follow up study

Monday, March 31, 2014
Women with PCOS should be tested regularly for early detection of abnormal glucose tolerance.

Read More

Gene dose effect between a fat mass and obesity associated polymorphism and body mass index was observed in Korean women with polycystic ovary syndrome but not in control women

Thursday, March 6, 2014
In women with polycystic ovary syndrome, the variant allele of Fat mass and obesity associated (FTO) rs9939609 was associated with increased body mass index.

Read More

Hyperandrogenemia is implicated in both the metabolic and reproductive morbidities of polycystic ovary syndrome

Thursday, February 20, 2014
A factor analysis identified multiple factors that are responsible for the abnormalities associated with PCOS. Hyperandrogenemia was a common underlying feature of the metabolic and reproductive abnormalities in women with PCOS.

Read More

Decreased inhibin B responses following recombinant human chorionic gonadotropin administration in normal women and women with polycystic ovary syndrome

Tuesday, December 31, 2013
In normal and polycystic ovary syndrome (PCOS) women, inhibin B production was decreased following recombinant hCG administration. These findings suggest that in PCOS women, androgen excess is not enhanced by LH-stimulated inhibin B production.

Read More

Follicle number not assessments of the ovarian stroma represents the best ultrasonographic marker of polycystic ovary syndrome

Tuesday, December 31, 2013
As a single metric, follicle number per ovary best predicts PCOS. Ovarian volume and follicle number per single cross-section, together, provide the closest level of diagnostic potential to follicle number per ovary alone. Stromal measurements have little to no diagnostic potential.

Read More

Pregnancy complications and metabolic disease in women with clomiphene citrate resistant anovulation randomized to receive laparoscopic electrocautery of the ovaries or ovulation induction with…

Tuesday, December 31, 2013
At 10-year follow-up, laparoscopic electrocautery in women with CC-resistant PCOS does not affect pregnancy complications or metabolic or cardiovascular disease later in life compared with ovulation induction with gonadotropins.

Read More

Polycystic ovary syndrome and nonalcoholic fatty liver in obese adolescents association with metabolic risk profile

Wednesday, November 27, 2013
The relationship between liver fat and metabolic risk was examined in obese adolescent girls with PCOS. This article demonstrates that worsening liver fat is associated with advancing age, increasing abdominal adiposity, worsening insulin sensitivity, and dyslipoproteinemia.

Read More

Predictive factors of health related quality of life in patients with polycystic ovary syndrome a structural equation modeling approach

Thursday, October 31, 2013
We discuss health-related quality of life in patients with polycystic ovary syndrome. Mediating factors, especially psychological distress, self-esteem, body image and sexual function play an important role and should be taken into consideration and adequately treated if present.

Read More

Dietary glycemic index is associated with less favorable anthropometric and metabolic profiles women with different phenotypes

Monday, September 30, 2013
Dietary glycemic index is increased in the classic polycystic ovary syndrome (PCOS) phenotype and associated with less favorable anthropometric and metabolic profiles. Obesity and classic PCOS phenotype are predictors of higher dietary glycemic index.

Read More

Prevalence of polycystic ovary syndrome in adolescents

Wednesday, July 31, 2013
Obesity was associated with PCOS in adolescents. Studies based on diagnosis codes only may underestimate the prevalence of PCOS and overestimate the magnitude of the association between obesity and PCOS.

Read More

Paracrine regulation of theca androgen production by granulosa cells in the ovary

Wednesday, July 31, 2013
Inhibin produced from granulosa cells is involved in the paracrine signal-mediating FSH stimulation of Cyp17 mRNA expression in theca cells. However, other paracrine factors from granulosa cells are also involved.

Read More

Use of clomiphene citrate in infertile women a committee opinion

Wednesday, July 31, 2013
This document reviews the mechanism of clomiphene citrate action, use in women with anovulatory and unexplained infertility, administration, side effects, and alternatives.

Read More

Phenotypic comparison of Caucasian and Asian women with polycystic ovary syndrome a cross sectional study

Friday, June 28, 2013
Caucasian and Asian women with polycystic ovary syndrome living in the same geographic region have a similar prevalence of hirsutism and other markers for androgen excess.

Read More

Is the fertile window extended in women with polycystic ovary syndrome Utilizing the SART registry to assess the impact of reproductive aging on live birth rate

Friday, June 28, 2013
Below the age of 40, women with polycystic ovary syndrome have higher clinical pregnancy and live-birth rates after in vitro fertilization compared with women with tubal factor infertility. After 40, despite a higher oocyte yield, there is no difference in pregnancy outcomes.

Read More

Introduction Back to the future origins of polycystic ovary syndrome

Friday, June 28, 2013
The ontogeny of PCOS is an early window on the nature of polycystic ovary syndrome.

Read More

Faster thrombin generation in women with polycystic ovary syndrome compared with healthy controls matched for age and body mass index

Tuesday, April 30, 2013
Young and overweight women with PCOS generated thrombin faster than paired controls matched for age and body mass index.

Read More

Seasonal effects on vitamin D status influence outcomes of lifestyle intervention in overweight and obese women with polycystic ovary syndrome

Tuesday, April 30, 2013
Overweight and obese women with polycystic ovary syndrome who increased their serum 25-hydroxyvitamin D levels more during lifestyle intervention achieved greater improvement in waist circumference and cholesterol.

Read More

Polycystic ovary syndrome offspring display increased oxidative stress markers comparable to gestational diabetes offspring

Friday, March 1, 2013
The present study demonstrated that in PCOS neonates, the oxidative stress status was similar to that of GDM neonates and strongly associated with their mothers’ oxidative status.

Read More

Birth weight and polycystic ovary syndrome in adult life A register based study on 523757 Danish women born 1973 to 1991

Friday, March 1, 2013
In a Danish national register study on 523,757 women, an association between birth weight 4,500 g and an increased risk of PCOS in adult life was found in offspring of nondiabetic women.

Read More

Psoriatic patients have an increased risk of polycystic ovary syndrome Results of a cross sectional analysis

Friday, March 1, 2013
This study is a cross-sectional analysis to determine the prevalence of PCOS in patients with psoriasis. The prevalence of PCOS in women with psoriasis is about 47%.

Read More

Subclinical hypothyroidism in young women with polycystic ovary syndrome An analysis of clinical hormonal and metabolic parameters

Monday, February 4, 2013
Young women with polycystic ovary syndrome and subclinical hypothyroidism present higher serum levels of low-density lipoprotein cholesterol with no changes in other lipid profile parameters, insulin resistance, or phenotypic manifestations.

Read More

Metformin decreases serum 8 hydroxy 2 deoxyguanosine levels in polycystic ovary syndrome

Monday, February 4, 2013
A double-blind, randomized, placebo-controlled trial on the effects of metformin on serum levels of 8-hydroxy-20-deoxyguanosine (8-OHdG) in women with polycystic ovary syndrome showed levels were statistically significantly reduced versus placebo.

Read More

Effect of bilateral oophorectomy on adrenocortical function in women with polycystic ovary syndrome

Monday, February 4, 2013
Adrenocortical responses before and after bilateral oophorectomy suggest that ovarian factors have a limited role in the etiology of adrenal androgen excess of polycystic ovary syndrome.

Read More

Predicting fertility with antimullerian hormone Is a cutoff value adequate

Thursday, November 29, 2012
Reflections on "Low concentration of circulating antimüllerian hormone is not predictive of reduced fecundability in young healthy women: a prospective cohort study" by Hagen et al.

Read More

CD4+CD28null T lymphocyte frequency a new marker of cardiovascular risk Relationship with polycystic ovary syndrome phenotypes

Thursday, November 29, 2012
Study of CD4+CD28null T-cell frequency, a new marker of cardiovascular risk, in the different PCOS phenotypes showed that CD4+CD28null frequency was significantly higher in the nonhyperandrogenic phenotype than in other phenotypes.

Read More

Adipose tissue insulin resistance in peripubertal girls with first degree family history of polycystic ovary syndrome

Thursday, November 29, 2012
Girls at risk for PCOS are mainly characterized by insulin resistance and resistance to insulin-induced lipolysis suppression. Predisposition to PCOS may thus be related to adipocyte dysfunction.

Read More

Opposing effects of dehydroepiandrosterone sulfate and free testosterone on metabolic phenotype in women with polycystic ovary syndrome

Thursday, November 1, 2012
In studying the association of adrenal and ovarian androgens with metabolic parameters in women with polycystic ovary syndrome, distinguishing between adrenal and ovarian hyperandrogenism is important to evaluate metabolic risk.

Read More

In search of the best combined oral contraceptive for treatment of polycystic ovary syndrome

Thursday, September 27, 2012
Reflections on "Comparative study of the therapeutic effects of oral contraceptive pills containing desogestrel, cyproterone acetate, and drospirenone in patients with polycystic ovary syndrome"

Read More

Retrieving oocytes from small non-stimulated follicles in polycystic ovary syndrome(PCOS): in vitro maturation (IVM) is not indicated in the new GnRH antagonist era

Friday, June 22, 2012
By effectively preventing OHSS, the antagonist protocol with GnRH-a trigger is a better option for treating women with PCOS than in vitro maturation (IVM).

Read More

Translate »