Western style diet with and without chronic androgen treatment alters the number structure and function of small antral follicles in ovaries of young adult monkeys

Friday, April 1, 2016
Consumption of a Western-style diet by female nonhuman primates with and without mildly elevated testosterone alters small antral follicle morphology, numbers, health, and RNA transcriptome.

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Ovarian morphology and function during growth hormone therapy of short girls born small for gestational age

Tuesday, November 25, 2014
We discuss how growth hormone treatment of girls born small for gestational age appeared to normalize ovarian morphology and function, while the long-term effects of growth hormone treatment on adult reproductive function remain unknown.

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Female cystic fibrosis mutation carriers and assisted reproductive technology Does carrier status affect reproductive outcomes

Monday, July 14, 2014
Female cystic fibrosis (CF) carrier status does not appear to impact the chance of achieving pregnancy with assisted reproductive technology (ART). Further research is needed to investigate whether positive CF carrier status affects fertility in a non-ART context.

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Differences in ovarian hormones in relation to parity and time since last birth

Sunday, June 1, 2014
Among cycling women, parous women have longer follicular phases and lower estradiol metabolite concentrations than nulliparous women. Estradiol, but not progesterone, metabolite concentrations are positively associated with time since last birth.

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Novel variants in the SOHLH2 gene are implicated in human premature ovarian failure

Monday, March 31, 2014
In large cohorts of Chinese and Serbian women with nonsyndromic premature ovarian failure, 11 novel heterozygous variants were identified in SOHLH2, with several predicted to be deleterious.

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Age at menarche a predictor of diminished ovarian function

Monday, September 30, 2013
There are significant associations between age at menarche and the risk of diminished ovarian function in infertile women.

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In women the reproductive harm of toxins such as tobacco smoke is reversible in 6 months basis for the olive tree hypothesis

Monday, September 30, 2013
The authors discuss the "olive tree" metaphor, which emphasizes and helps promote the concept that reproductive damage done by environmental toxins such as tobacco smoke is not definitive.

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NR5A1 SF1 gene variants in a group of 26 young women with XX primary ovarian insufficiency

Monday, February 4, 2013
In a primary ovarian insufficiency group, we identified one mutation and a frequent variant of the NR5A1/SF-1 gene. This work confirms the important role of steroidogenic factor 1 in ovarian function.

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Improvement of hyperandrogenism and hyperinsulinemia during pregnancy in women with polycystic ovary syndrome: possible effect in the ovarian follicular mass of their daughters

Monday, June 4, 2012
Lowering of androgens and insulin during pregnancy in mothers with polycystic ovary syndrome reduces anti-Mullerian hormone levels in their daughters, which might reflect a decrease in their follicular mass.

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Administration of visfatin during superovulation improves developmental competency of oocytes and fertility potential in aged female mice

Friday, May 4, 2012
Coadministration of visfatin during superovulation improved ovarian expression of visfatin and vascular endothelial growth factor, developmental competency of oocytes, and fertility in aged female mice.

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