Treatment of infertility and the risk of ovarian cancer Are the data reassuring

Tuesday, March 1, 2016

Author:
Richard J. Paulson, M.D.…

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Treatment of infertility does not increase the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation

Tuesday, March 1, 2016
These findings suggest that treatment for infertility does not significantly increase the risk of ovarian cancer among women with a BRCA mutation.

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Evidence of a genetic link between endometriosis and ovarian cancer

Tuesday, December 29, 2015
There is a clear genetic link between endometriosis and risk of ovarian cancer, especially for the highgrade serous and clear cell histotypes.

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Endometriosis and ovarian cancer Potential benefits and harms of screening and risk reducing surgery

Tuesday, September 29, 2015
This review critically appraises published studies for and against the endometriosis–ovarian cancer link and attempts to weigh the potential benefits and harms of screening and risk-reducing surgery accordingly.

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Fertility treatments and invasive epithelial ovarian cancer risk in Jewish Israeli BRCA1 or BRCA2 mutation carriers

Wednesday, April 29, 2015
In a cohort of 1,073 BRCA mutation carriers, fertility treatments were not found to be risk modifiers for invasive epithelial ovarian cancer.

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Robotic assisted surgery in gynecologic oncology

Tuesday, August 12, 2014
A review of the role of robotic surgery in the management of various gynecologic malignancies, with an emphasis on novel robotic innovations, special patient populations, cost effectiveness, and fellowship training.

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Malignant transformation of endometriosis and its clinical significance

Wednesday, July 30, 2014
Future efforts should be focused on developing effective and noninvasive screening tools to identify patients with endometriosis and possible nonsurgical treatment options, such as long-term tolerable suppressive medical therapy.

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Tubal ligation hysterectomy unilateral oophorectomy and risk of ovarian cancer in the Nurses Health Studies

Wednesday, June 25, 2014
Tubal ligation, hysterectomy, and unilateral oophorectomy were independently associated with lower risks of ovarian cancer. The associations with tubal ligation and hysterectomy are stronger for nonserous tumors.

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Prophylactic salpingectomy in premenopausal women at low risk for ovarian cancer risk reducing or risky

Wednesday, November 27, 2013
Reflections on "Short-term effects of salpingectomy during laparoscopic hysterectomy on ovarian reserve: a pilot randomized controlled trial" by Findley et al.

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Ovulation inducing drugs and ovarian cancer risk results from an extended followup of a large United States infertility cohort

Wednesday, November 27, 2013
Our findings were generally reassuring in not confirming a link between ovulation-inducing drugs and ovarian cancer; risk was increased, however, among women who, despite having used clomiphene citrate, remained nulligravid.

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Proteomic Biomarkers for Ovarian Cancer risk in Women with Polycystic Ovary Syndrome A Systematic Review and Biomarker Database Integration

Thursday, November 29, 2012
The biomarkers calreticulin, fibrinogen-γ, superoxide dismutase, vimentin, malate dehydrogenase, and lamin B2 could help improve our understanding of the links between polycystic ovary syndrome (PCOS) and ovarian cancer (OC) and could potentially be used to identify subgroups of women with PCOS at increased risk of OC. More studies are required to further evaluate the role these biomarkers play in women with PCOS and OC.

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Best Practices of ASRM and ESHRE A Journey through Reproductive Medicine

Thursday, November 29, 2012
ASRM and ESHRE held their first joint meeting on the hottest topics in the field. Although different opinions and approaches sometimes exist, there was more commonality than divergence of opinion.

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Duarte galactose-1-phosphate uridyl transferase genotypes are not associated with ovarian cancer risk

Monday, June 18, 2012
This study suggests that Duarte1 and Duarte2 genotypes do not appear to play a role in the association from galactose intake, possible ovarian dysfunction, and the link with ovarian cancer.

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