Recommendations for development of an emergency plan for in vitro fertilization programs A committee opinion

Sunday, May 1, 2016
All in vitro fertilization programs and clinics should have plans for the protection of fresh and cryopreserved human tissue and continuation of patient care in the event of an emergency or natural disaster.

Read More

Is oocyte meiotic spindle morphology associated with embryo ploidy A prospective cohort study

Friday, April 1, 2016
This study demonstrates for the first time that oocytes with normal spindle morphology are more likely to produce euploid embryos compared with oocytes with translucent or no visible meiotic spindles.

Read More

Hepatitis B surface antigen in oocytes and embryos may not result in vertical transmission to offspring of hepatitis B virus carriers

Friday, April 1, 2016
Children from oocytes and embryos infected with hepatitis B virus (HBV) were not chronically infected after birth; the HBsAg in oocytes and embryos may not result in vertical transmission.

Read More

Diagnostic evaluation of the infertile female A committee opinion

Monday, June 1, 2015
This committee opinion assesses current methods and procedures for evaluation of infertile women.

Read More

Oocyte environment Follicular fluid and cumulus cells are critical for oocyte health

Friday, January 30, 2015
Bidirectional somatic cell–oocyte interactions are essential to create a dynamic intrafollicular microenvironment that fosters development of a healthy oocyte and preimplantation embryo.

Read More

Oocyte competency is the key to embryo potential

Friday, January 30, 2015
The oocyte is the major determinant of embryo developmental competence. Technology has improved the noninvasive assessment of oocyte quality. Analysis of polar body DNA may provide insight into the prediction of embryo developmental competence.

Read More

Simple perfusion apparatus for manipulation tracking and study of oocytes and embryos

Monday, December 29, 2014
A simple perfusion apparatus was designed, constructed, and tested for safely and securely culturing, testing, and visualizing oocytes and embryos for longitudinal analysis with minimal handling.

Read More

Melatonin and the circadian system Contributions to successful female reproduction

Wednesday, July 30, 2014
Both circadian rhythms and melatonin are important for optimal function of the peripheral reproductive system. In addition to synchronizing rhythms, melatonin may protect the ovary, especially the oocyte and the placenta, from oxidative damage.

Read More

Ovarian endometriomas and oocyte quality insights from in vitro fertilization cycles

Monday, March 31, 2014
In women with unilateral unoperated endometriomas undergoing IVF, ovarian responsiveness and oocyte developmental competence did not differ between the affected and intact gonads.

Read More

Preliminary investigation of the impact of anticentromere antibody on oocyte maturation and embryo cleavage

Wednesday, November 27, 2013
Decreased percentage of mature oocytes and rate of embryo cleavage were found in the ACA[+]/ANA[+] group as compared with the ACA[]/ANA[+] group.

Read More

Chronic exposure to a low concentration of bisphenol A during follicle culture affects the epigenetic status of germinal vesicles and metaphase II oocytes

Wednesday, November 27, 2013
Chronic follicle culture exposure to low bisphenol A affects imprinting and posttranslational histone modifications in mouse oocytes, epigenetic aberrations that might contribute to aneuploidy, altered gene expression, and epigenetic disease.

Read More

Comparative gene expression profiling of adult mouse ovary derived oogonial stem cells supports a distinct cellular identity

Thursday, October 31, 2013
Oogonial stem cells exhibited a gene expression profile partially overlapping with, but distinct from, other stem cells and germ cells, and they showed altered numbers during the reproductive cycle inversely related to meiotic commitment.

Read More

Multidrug resistant transport activity protects oocytes from chemotherapeutic agents and changes during oocyte maturation

Thursday, October 31, 2013
Oocytes have a vast repertoire of multidrug-resistant transporters. These protective effluxers change overall activity during maturation, and inhibition of these transporters increases cell susceptibility to toxicants.

Read More

Bone morphogenetic protein 4 promotes mammalian oogonial stem cell differentiation via Smad1 5 8 signaling

Thursday, October 31, 2013
Bone morphogenetic protein 4 increased oocyte formation from adult mouse ovary-derived oogonial stem cells via activation of Smad1/5/8 signaling and key meiosis commitment genes.

Read More

In women the reproductive harm of toxins such as tobacco smoke is reversible in 6 months basis for the olive tree hypothesis

Monday, September 30, 2013
The authors discuss the "olive tree" metaphor, which emphasizes and helps promote the concept that reproductive damage done by environmental toxins such as tobacco smoke is not definitive.

Read More

Influence of oocyte dysmorphisms on blastocyst formation and quality

Friday, August 30, 2013
Individual identification of oocyte dymorphisms may be a prognostic tool for blastocyst development and quality.

Read More

Polar body biopsy

Friday, August 30, 2013
Polar body biopsy combined with array comparative genomic hybridization allows detection of maternal chromosomal aberrations. Although it has limitations, it can be seen as an alternative to blastomere and trophectoderm biopsy.

Read More

New approach in patients with polycystic ovaries lessons for everyone

Thursday, March 28, 2013
In vitro maturation, including FSH priming, recovery of oocytes from 12-mm follicles, and using single blastocyst transfer, is safe and provides pregnancy rates up to 40% in patients with PCO.

Read More

Cryoprotectants up regulate the expression of mouse oocyte AQP7 which facilitates water diffusion during cryopreservation

Thursday, March 28, 2013
Dimethylsulfoxide may up-regulate AQP7 expression in mouse oocytes by both osmolarity-dependent and osmolarity-independent pathways, and up-regulation of AQP7 facilitates water diffusion in mouse oocytes.

Read More

Epigenetic disturbances in in vitro cultured gametes and embryos Implications for human assisted reproduction

Friday, March 1, 2013
Despite accumulating evidence in animal models that in vitro culture of oocytes and embryos can interfere with epigenetic genome reprogramming, little is known about the epigenetic risks of human assisted reproductive technologies.

Read More

The aging oocyte Can mitochondrial function be improved

Wednesday, January 2, 2013
We describe the role of mitochondrial dysfunction in ovarian senescence and suggest a treatment to improve reproductive outcome with mitochondrial nutrients.

Read More

Recommendations for gamete and embryo donation A committee opinion

Wednesday, January 2, 2013
This document provides the latest recommendations for evaluation of potential sperm, oocyte, and embryo donors.

Read More

The next (re)generation of ovarian biology and fertility in women: is current science tomorrow’s practice?

Thursday, June 28, 2012
We present an overview of gametogenesis from stem cells, with emphasis on generation of human oocytes, future research objectives for this area of work, and potential clinical applications involving human oogonial stem cells.

Read More

Diagnostic evaluation of the infertile female: a committee opinion

Tuesday, June 12, 2012
This committee opinion assesses current methods and procedures for evaluation of the infertile female.

Read More

Adiponectin and its receptors modulate granulosa cell and cumulus cell functions, fertility, and early embryo development in the mouse and human

Thursday, June 7, 2012
Adiponectin receptors, expressed in mouse and human granulosa cells and cumulus cell-oocyte complexes, mediate differential gene expression in mouse cumulus cells versus granulosa cells and enhance oocyte maturation/embryo development.

Read More

Identification of phosphodiesterase 9A as a cyclic guanosine monophosphate–specific phosphodiesterase in germinal vesicle oocytes: a proposed role in the resumption of meiosis

Thursday, June 7, 2012
Phosphodiesterase 9A (PDE9A), a cyclic guanosine monophosphate–specific phosphodiesterase detectable in germinal vesicle oocytes, likely promotes maturation events upstream of PDE3A, making it a candidate target for nonhormonal contraception.

Read More

Strain-specific spontaneous activation during mouse oocyte maturation

Thursday, June 7, 2012
Oocyte spontaneous activation, an irregularity of the cell cycle that can lead to ovarian teratomas, has genetic variation among inbred mouse strains, and is sensitive to the culture environment.

Read More

A characterization of the relationship of ovarian reserve markers with age

Monday, June 4, 2012
Antral follicle count and antimullerian hormone rate of decline is similar to histologic oocyte loss.

Read More

Full in vitro fertilization laboratory mechanization: toward robotic assisted reproduction?

Wednesday, May 30, 2012
Technologies related to automation, such as nonsubjective sperm selection, oocyte fertilization, and embryo culture and monitoring, are available, and this means that sample preparation, chemical or biologic reactions, and data collection could be integrated.

Read More

Phospholipase C-ζ-induced Ca2+ oscillations cause coincident cytoplasmic movements in human oocytes that failed to fertilize after intracytoplasmic sperm injection

Wednesday, May 23, 2012
PLCz-induced Ca2+ oscillations in human oocytes that failed to fertilize after intracytoplasmic sperm injection cause small, discrete movements in the cytoplasm that provide a noninvasive measure of the pattern of Ca2+ transients during activation.

Read More

Translate »