Higher PDCD4 expression is associated with obesity insulin resistance lipid metabolism disorders and granulosa cell apoptosis in polycystic ovary syndrome

Sunday, May 1, 2016
In polycystic ovary syndrome (PCOS), higher PDCD4 expression promotes obesity, insulin resistance, lipid metabolism disorders, and induced granulosa cell apoptosis, which is an independent risk factor for PCOS.

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Body mass index physical activity and fecundability in a North American preconception cohort study

Thursday, April 7, 2016

Authors:
Craig J. McKinnon, M.P.H., Elizabeth E.…

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Sociocultural influences on fertility in the Middle East The role of parental consanguinity obesity and vitamin D deficiency

Thursday, April 7, 2016

Authors:
Julia K. Bosdou, M.D., M.Sc., Ph.D., Efstratios M.…

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Survey assessing obesity policies for assisted reproductive technology in the United States

Tuesday, March 1, 2016
We discuss the different policies of centers regarding obesity and access to assisted reproductive technology.

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Pregnancy outcomes decline with increasing body mass index Analysis of 239127 fresh autologous in vitro fertilization cycles from the 2008 2010 Society for Assisted Reproductive Technology registry

Tuesday, March 1, 2016
Success rates in fresh autologous IVF cycles, including those done for specifically polycystic ovary syndrome or male-factor infertility, are highest in those with low and normal body mass indexes.

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Pregnancy outcomes decline with increasing recipient body mass index An analysis of 22317 fresh donor recipient cycles from the 2008 2010 Society for Assisted Reproductive Technology Clinic Outcome Reporting System registry

Monday, February 1, 2016
Success rates in donor in vitro fertilization cycles are highest in recipients with low and normal body mass index.

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Influence of adrenal hyperandrogenism on the clinical and metabolic phenotype of women with polycystic ovary syndrome

Friday, February 27, 2015
The presence of adrenal hyperandrogenism in women with polycystic ovary syndrome is associated with reduced insulin sensitivity and increased blood pressure, but may have a beneficial impact on the lipid profile.

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Association of body mass index with embryonic aneuploidy

Friday, February 27, 2015
Body mass index was not associated with the number or percent of euploid embryos in patients undergoing 24-chromosome pre-implantation genetic screening.

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Effect of male and female body mass index on pregnancy and live birth success after in vitro fertilization

Friday, January 30, 2015
No association between male and female BMI, individually or combined, and IVF success was found after accounting for important confounding factors, including male and female age, partner BMI, and parity.

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Effects of resveratrol on ovarian response to controlled ovarian hyperstimulation in ob ob mice

Friday, January 30, 2015
This study suggests the potential use of resveratrol to improve the ovulatory response to controlled ovarian hyperstimulation in nonobese females and to preserve the ovarian reserve in obesity-related conditions.

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Maternal undernutrition induces premature reproductive senescence in adult female rat offspring

Monday, December 29, 2014
An adverse uterine nutritional environment during pregnancy results in premature reproductive senescence in adult rats.

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Elevated non esterified fatty acid concentrations during in vitro murine follicle growth alter follicular physiology and reduce oocyte developmental competence

Tuesday, November 25, 2014
Long-term elevated NEFA concentrations, typical in metabolic disorders, such as obesity or type 2 diabetes, alter follicular growth and physiology, ultimately resulting in reduced oocyte developmental competence in vitro.

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Frequency of euploid miscarriage is increased in obese women with recurrent early pregnancy loss

Wednesday, July 30, 2014
Based on a cohort of 372 women with a history of recurrent early pregnancy loss, obesity was associated with euploid miscarriage, which is a known risk factor for subsequent miscarriage.

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Diet induced maternal obesity alters ovarian morphology and gene expression in the adult mouse offspring

Wednesday, June 11, 2014
Ovaries of mouse offspring from high–fat–fed obese dams have reduced follicular population and altered gene expression, which could impact their reproductive potential.

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A retrospective cohort study to evaluate the impact of meaningful weight loss on fertility outcomes in an overweight population with infertility

Wednesday, April 30, 2014
Overweight patients with infertility who underwent weight loss counseling and achieved meaningful weight loss (10%) had improved live birth rates compared with those who did not.

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Gene dose effect between a fat mass and obesity associated polymorphism and body mass index was observed in Korean women with polycystic ovary syndrome but not in control women

Thursday, March 6, 2014
In women with polycystic ovary syndrome, the variant allele of Fat mass and obesity associated (FTO) rs9939609 was associated with increased body mass index.

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Obese fathers metabolic state adiposity and reproductive capacity indicate a sons reproductive health

Thursday, February 20, 2014
Diet and exercise interventions in obese founder males improve the reproductive health of male offspring, with a father’s metabolic and reproductive status predicting his son’s reproductive health.

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Polycystic ovary syndrome and nonalcoholic fatty liver in obese adolescents association with metabolic risk profile

Wednesday, November 27, 2013
The relationship between liver fat and metabolic risk was examined in obese adolescent girls with PCOS. This article demonstrates that worsening liver fat is associated with advancing age, increasing abdominal adiposity, worsening insulin sensitivity, and dyslipoproteinemia.

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Association of blood type and patient characteristics with ovarian reserve

Wednesday, November 27, 2013
No relationship could be demonstrated between blood type and risk of diminished ovarian reserve in an analysis of 305 patients undertaking in vitro fertilization.

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Serum antimüllerian hormone in response to dietary management and or physical exercise in overweight obese women with polycystic ovary syndrome secondary analysis of a randomized controlled trial

Monday, September 30, 2013
Randomized intervention with diet, but not exercise or combined intervention, reduces serum AMH levels in association with decreased T in obese women with PCOS, whereas weight loss has no significant influence.

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Prevalence of polycystic ovary syndrome in adolescents

Wednesday, July 31, 2013
Obesity was associated with PCOS in adolescents. Studies based on diagnosis codes only may underestimate the prevalence of PCOS and overestimate the magnitude of the association between obesity and PCOS.

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Seasonal effects on vitamin D status influence outcomes of lifestyle intervention in overweight and obese women with polycystic ovary syndrome

Tuesday, April 30, 2013
Overweight and obese women with polycystic ovary syndrome who increased their serum 25-hydroxyvitamin D levels more during lifestyle intervention achieved greater improvement in waist circumference and cholesterol.

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Seminal plasma adipokine levels are correlated with functional characteristics of spermatozoa

Thursday, March 28, 2013
Obesity has an impact on semen quality, and adipokines appear to influence semen parameters potentially in conjunction with body mass index.

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Knowledge about factors that influence fertility among Australians of reproductive age A population based survey

Monday, February 4, 2013
There are considerable knowledge gaps among Australians of reproductive age about the impact on fertility of age, weight, smoking, and timing of sex.

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Overweight men with nonobstructive azoospermia have worse pregnancy outcomes after microdissection testicular sperm extraction

Monday, February 4, 2013
Overweight men have lower clinical pregnancy rate after microdissection testicular sperm extraction and intracytoplasmic sperm injection compared with men with normal weight. Men with body mass index >43 kg/m2 did not contribute to any pregnancies despite successful sperm retrieval.

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Size does matter Higher body mass index may mean lower pregnancy rates for microscopic testicular sperm extraction

Monday, February 4, 2013
Reflections on "Overweight men with nonobstructive azoospermia have worse pregnancy outcomes following microdissection testicular sperm extraction" by Ramasamy et al.

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Antimüllerian hormone levels are independently related to ovarian hyperandrogenism and polycystic ovaries

Thursday, June 28, 2012
Antimullerian hormone (AMH) levels correlate independently with polycystic ovaries and ovarian hyperandrogenism. AMH levels in PCOS overlap those in volunteers with normal-variant polycystic ovaries. Only substantial AMH elevations are diagnostic of PCOS.

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The effect of body mass index on the outcomes of first assisted reproductive technology cycles

Thursday, June 28, 2012
Patients with a BMI over 30 have up to 68% lower odds of having a live birth following their first ART cycle.

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Adipose expression of adipocytokines in women with polycystic ovary syndrome

Thursday, June 7, 2012
In a cross-sectional study of women with and without polycystic ovary syndrome (PCOS), obesity but not PCOS affected the expression of adipose expression and plasma levels of adipocytokines.

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Circulating Vitamin D Correlates with Serum Anti-Mullerian Hormone Levels in Late Reproductive-Aged Women: Women’s Interagency HIV Study

Thursday, June 7, 2012
Serum 25-hydroxyvitamin D levels are positively correlated with serum antim€ullerian hormone levels in latereproductive-aged women (40 years old).

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