Expression of microtubule associated protein 2 and synaptophysin in endometrium High levels in deep infiltrating endometriosis lesions

Monday, February 1, 2016
Nerve growth factor, microtubule associated protein 2, and synaptophysin messenger RNAs and proteins are expressed in healthy endometrium and in endometriosis, being highest in deep lesions.

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Dienogest inhibits nerve growth factor expression induced by tumor necrosis factor α or interleukin 1β

Friday, January 31, 2014
Nerve growth factor is one of the key mediators that generates the pain associated with endometriosis. Dienogest inhibited NGF expression induced by TNF-α or IL-1β in human endometrial epithelial cells.

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