Tuesday, March 1, 2016
A discussion of the enhancing factors contributing to gamete competence and the mitigating factors reducing gamete (and therefore embryo) potential promise to reduce the number of euploid embryos failing to produce normal viable deliveries.
Tuesday, September 1, 2015
Higher mitochondrial DNA content in euploid human embryos is related to poor implantation potential and may be indicative of reduced metabolic fuel during oocyte maturation.
Monday, July 14, 2014
A novel microarray platform was developed offering the possibility of combined aneuploidy screening, genetic fingerprinting, and mitochondrial DNA (mtDNA) assessment of embryos. Associations between mtDNA and maternal age are reported.
Friday, June 28, 2013
Mitochondria are significantly activated in growthrestricted fetuses, which may be a response to adverse intrauterine environments rather than to genetic factors.
Thursday, November 1, 2012
Blastocyst PGD of mutation load and gender was applied for the first time. Results demonstrate that the trophectoderm is predictive of inner cell mass and newborn mutation loads and that simultaneous gender selection can be used to reduce the transgenerational risk of inheritance.