Tuesday, March 1, 2016
Seminal plasma proteome reflects sperm mitochondrial defects, acrosome alterations, and DNA fragmentation. Altered proteins and biological functions were identified, and a panel of biomarkers was proposed for sperm functional traits.
Tuesday, September 1, 2015
Coenzyme Q (CoQ)-dependent mitochondrial activity in granulosa cells reduces with aging and is restored via supplementation, indicating that functional CoQ10 deficit is the main underlying cause for oxidative phosphorylation dysfunction.
Monday, June 1, 2015
We discuss whether advanced maternal age has long-term effects through inheritance of the mitochondrial DNA, apart from the immediate consequences of maternal age on reproduction.
Friday, January 30, 2015
In subjects with surgically confirmed endometriosis, cumulus cells obtained after IVF stimulation and oocyte retrieval have decreased mitochondrial activity compared with controls.
Monday, December 29, 2014
Through a case-control study, the GRIM-19 deficiency in the villus was found may be associated with missed abortion via increasing apoptosis and affecting angiogenesis.
Tuesday, December 31, 2013
The exchange of nuclear genetic material between oocytes and embryos offers a novel reproductive option for the prevention of inherited mitochondrial diseases.
Friday, May 31, 2013
Mitochondrial displacement (D-) loop alterations may constitute an inheritable risk factor for endometriosis. The analysis of D-loop alterations might help to identify patients at high risk for disease outcome.
Wednesday, January 2, 2013
We describe the role of mitochondrial dysfunction in ovarian senescence and suggest a treatment to improve reproductive outcome with mitochondrial nutrients.
Thursday, June 7, 2012
The mitochondrial OXPHOS function in the granulosa luteal cells is unaffected by aging or diminishment of the ovarian response.