Association between the seminal plasma proteome and sperm functional traits

Tuesday, March 1, 2016
Seminal plasma proteome reflects sperm mitochondrial defects, acrosome alterations, and DNA fragmentation. Altered proteins and biological functions were identified, and a panel of biomarkers was proposed for sperm functional traits.

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Coenzyme Q dependent mitochondrial respiratory chain activity in granulosa cells is reduced with aging

Tuesday, September 1, 2015
Coenzyme Q (CoQ)-dependent mitochondrial activity in granulosa cells reduces with aging and is restored via supplementation, indicating that functional CoQ10 deficit is the main underlying cause for oxidative phosphorylation dysfunction.

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Potential long term risks associated with maternal aging the role of the mitochondria

Monday, June 1, 2015
We discuss whether advanced maternal age has long-term effects through inheritance of the mitochondrial DNA, apart from the immediate consequences of maternal age on reproduction.

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Endometriosis may be associated with mitochondrial dysfunction in cumulus cells from subjects undergoing in vitro fertilization intracytoplasmic sperm injection as reflected by decreased adenosine triphosphate production

Friday, January 30, 2015
In subjects with surgically confirmed endometriosis, cumulus cells obtained after IVF stimulation and oocyte retrieval have decreased mitochondrial activity compared with controls.

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Expression of GRIM 19 in missed abortion and possible pathogenesis

Monday, December 29, 2014
Through a case-control study, the GRIM-19 deficiency in the villus was found may be associated with missed abortion via increasing apoptosis and affecting angiogenesis.

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Three parent in vitro fertilization Gene replacement for the prevention of inherited mitochondrial diseases

Tuesday, December 31, 2013
The exchange of nuclear genetic material between oocytes and embryos offers a novel reproductive option for the prevention of inherited mitochondrial diseases.

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Mitochondrial displacement loop alterations are associated with endometriosis

Friday, May 31, 2013
Mitochondrial displacement (D-) loop alterations may constitute an inheritable risk factor for endometriosis. The analysis of D-loop alterations might help to identify patients at high risk for disease outcome.

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The aging oocyte Can mitochondrial function be improved

Wednesday, January 2, 2013
We describe the role of mitochondrial dysfunction in ovarian senescence and suggest a treatment to improve reproductive outcome with mitochondrial nutrients.

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Human granulosa luteal cell OXPHOS function is not affected by age or ovarian response

Thursday, June 7, 2012
The mitochondrial OXPHOS function in the granulosa luteal cells is unaffected by aging or diminishment of the ovarian response.

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