Interaction of apolipoprotein E gene polymorphisms on miscarriage risk in black and white American women

Wednesday, June 1, 2016
We investigated a biracial cohort of women at the end of their reproductive life. Carrying the apolipoprotein E*2 allele was a risk factor for pregnancy loss only in white women.

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Uterine septum A guideline

Wednesday, May 18, 2016

Authors:
Practice Committee of the American Society for Reproductive Medicine

Abstract:

The purpose of this guideline is to review the literature regarding septate uterus and determine optimal indications and methods of treatment for it.…

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Antimüllerian hormone and pregnancy loss from the Effects of Aspirin in Gestation and Reproduction trial

Friday, April 1, 2016
Lower and higher antimullerian hormone levels are not associated with human chorionic gonadotropin- detected or clinical pregnancy loss in unassisted conceptions in women with a history of pregnancy loss.

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Risk of miscarriage in women with endometriosis Insights from in vitro fertilization cycles

Tuesday, March 29, 2016

Authors:
Marta Leonardi, M.D., Enrico Papaleo, M.D., Marco Reschini, M.Sc., Luca Pagliardini, M.D., Laura Benaglia, M.D., Giorgio Candotti, M.D., Paola Viganó, D.Sc., Ph.D., Lavinia Quaranta, M.D., Maria Munaretto, M.D., Massimo Candiani, M.D., Paolo Vercellini, M.D., Edgardo Somigliana, M.D.…

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First trimester pregnancy loss after fresh and frozen in vitro fertilization cycles

Tuesday, March 1, 2016
The magnitudes of risk for early pregnancy loss after in vitro fertilization for all infertility diagnoses were small. The risks were similar when transferring similar quality embryos in fresh or frozen cycles.

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Lifestyle and pregnancy loss in a contemporary cohort of women recruited before conception The LIFE Study

Wednesday, February 24, 2016

Authors:
Germaine M. Buck Louis, Ph.D., M.S., Katherine J.…

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Inflammosome in the human endometrium Further step in the evaluation of the maternal side

Tuesday, December 29, 2015
The recurrent pregnancy loss endometrium shows an increased expression of inflammasome NALP-3 and ASC protein, an increased activation of caspase-1, and increased levels of IL-1b and IL-18. These are possible signs of an abnormal endometrial receptivity.

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Spontaneous fertility and IVF outcome The new evidence of HPV sperm infection

Tuesday, December 29, 2015
This clinical study demonstrates a significant association between HPV sperm infection, reduced pregnancy rates, and higher miscarriage rates in couples undergoing assisted reproduction.

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Role of spermatozoa in the etiology of miscarriage

Tuesday, December 29, 2015

Author:
Richard Bronson, M.D.…

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Increased chromosome 16 disomy rates in human spermatozoa and recurrent spontaneous abortions

Thursday, October 29, 2015
Meiotic errors involving chromosome 16 of paternal origin seem to have an equally important influence on to the overall fetal aneuploidy rate compared with maternal chromosome 16 disomy.

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Pregnancy outcomes in women with chronic endometritis and recurrent pregnancy loss

Tuesday, September 29, 2015
Chronic endometritis is prevalent among women with recurrent pregnancy loss and may contribute to poor pregnancy outcomes.

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Loop electrosurgical excision procedure and risk of miscarriage

Monday, March 30, 2015
Women with a time interval from LEEP to pregnancy of <12 months are at increased risk for miscarriage.

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Loop electrosurgical excision procedure A risk for spontaneous abortion

Monday, March 30, 2015
Reflections on "Proportion of cervical excision for cervical intraepithelial neoplasia as a predictor of pregnancy outcomes" by Kyrgiou et al.

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Preconceptional thyroid stimulating hormone levels and outcomes of intrauterine insemination among euthyroid infertile women

Monday, December 29, 2014
Among euthyroid patients undergoing IUI, TSH level was not associated with cycle parameters or clinical pregnancy rate. TSH level was inversely related to the odds of spontaneous abortion.

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Müllerian duct anomalies diagnosed by saline contrast sonohysterography Prevalence in a general population

Wednesday, July 30, 2014
The prevalence of uterine mullerian duct anomalies has not previously been studied in a randomly selected general population. By saline contrast sonohysterography a prevalence of 9.8% was found.

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Conjugated bisphenol A in maternal serum in relation to miscarriage risk

Wednesday, June 25, 2014
Conjugated bisphenol A level in maternal serum at the time of missed menses is associated with increased risk of euploid and aneuploid miscarriage in an infertile population.

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Whether sperm deoxyribonucleic acid fragmentation has an effect on pregnancy and miscarriage after in vitro fertilization intracytoplasmic sperm injection A systematic review and metaanalysis

Friday, June 20, 2014
This systematic review and meta-analysis showed that high sperm DNA fragmentation was related to lower pregnancy rates in IVF but not in ICSI cycles, whereas it was associated to higher miscarriage rates in both IVF and ICSI cycles.

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Methylation status of human chorionic gonadotropin beta subunit promoter and TFAP2A expression as factors regulating CGB gene expression in placenta

Wednesday, June 11, 2014
During pregnancy, regulation of the expression of human chorionic gonadotropin beta subunit genes correlates with methylation of their promoters and TFAP2A expression.

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Risk factors for early miscarriage among Chinese a hospital based case control study

Sunday, June 1, 2014
In a case-control study of early miscarriage among Chinese women, previous induced abortion, working night shifts, and frequently staying up late are associated risk factors.

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Miscarriage chromosome testing Utility of comparative genomic hybridization with reflex microsatellite analysis in preserved miscarriage tissue

Wednesday, April 30, 2014
This observational study shows that comparative genomic hybridization and reflex microsatellite analysis are effective DNA technologies to determine chromosome results of preserved miscarriage tissue.

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Current clinical irrelevance of luteal phase deficiency A committee opinion

Sunday, March 30, 2014
This committee opinion addresses controversies regarding the diagnosis and potential treatment of luteal phase inadequacy.

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Female age related fertility decline

Thursday, February 20, 2014
Education and enhanced awareness of the effect of age on fertility is essential in counseling the patient who desires pregnancy.

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Reliability of 46 XX results on miscarriage specimens A review of 1222 first trimester miscarriage specimens

Tuesday, December 31, 2013
Maternal cell contamination often obscures accurate chromosome analysis of miscarriages, but testing can differentiate the maternal from fetal genome, thus improving detection of the true karyotype of pregnancy tissue.

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Prolactin and proinflammatory cytokine expression at the fetomaternal interface in first trimester miscarriage

Friday, June 28, 2013
Impaired prolactin (PRL) expression in samples from miscarriages and the particular expression of the proinflammatory cytokines suggest the pivotal role of PRL in vital pregnancies, reciprocally affected by interleukin-2 expression.

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Genetic variation in tissue inhibitors of metalloproteinases as a risk factor for idiopathic recurrent spontaneous abortion

Friday, May 31, 2013
There were no statistically significant differences in the distribution of genotype and allele frequencies of tissue inhibitors of metalloproteinases 1, 2, 3, and 4 gene polymorphisms between idiopathic recurrent spontaneous abortion couples and control subjects.

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A randomized clinical trial to evaluate the effect of granulocyte macrophage colony stimulating factor GM CSF in embryo culture medium for in vitro fertilization

Tuesday, April 30, 2013
In a prospective randomized study, addition of recombinant granulocyte-macrophage colony-stimulating factor to IVF embryo culture medium was found to increase ongoing implantation rate at gestational week 12 and live birth rate.

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Y chromosome azoospermia factor region microdeletions are not associated with idiopathic recurrent spontaneous abortion in a Slovenian population association study and literature review

Tuesday, April 30, 2013
Azoospermia factor region microdeletions were not detected in Slovenian men with IRSA. Our comparisons with previous studies show that Y chromosome microdeletions are most likely not associated with IRSA.

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Definitions of infertility and recurrent pregnancy loss A committee opinion

Wednesday, January 2, 2013
This document contains the definitions for infertility and recurrent pregnancy loss as defined by the Practice Committee of the American Society for Reproductive Medicine.

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Early pregnancy failure Beware of the pitfalls of modern management

Thursday, November 1, 2012
Modern management of early pregnancy failure has reduced morbidity and mortality, but new issues such as missed diagnosis and inappropriate use of methotrexate have emerged.

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When is a pregnancy nonviable What criteria should be used to define miscarriage

Thursday, November 1, 2012
Correctly diagnosing miscarriage is a fundamental decision. Systematic review of the evidence suggests criteria to determine early pregnancy viability are flawed and may lead to inadvertent termination. Recent publications suggest more conservative guidance is needed.

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