Sunday, May 1, 2016
Four circulating miRNAs (miR-320b, miR-146b-5p, miR-221-3p, miR-559) were up-regulated and one miRNA (miR-101-3p) was down-regulaed in unexplained recurrent spontaneous abortion (URSA). These circulating microRNAs may be involved in URSA pathogenesis and provide a promising new diagnostic biomarker for URSA.
Tuesday, April 12, 2016
Emine Cosar, M.D., Ramanaiah Mamillapalli, Ph.D., Gulcin Sahin Ersoy, M.D., SihYun Cho, M.D., Benjamin Seifer, B.S., Hugh S.…
Monday, February 1, 2016
The authors validated protocols that produce reliable and reproducible gene-expression profiles of individual human oocytes.
Thursday, July 30, 2015
A molecular karyotype can be obtained from genomic deoxyribonucleic acid isolated from the blastocoel fluid, which may provide insight into embryonic development and demonstrate the potential for future less invasive preimplantation genetic testing.
Monday, March 31, 2014
Genome-wide lncRNA expression patterns of ovarian endometriosis tissue are profiled by microarray, compared with paired eutopic endometrium. Nearly 1,000 lncRNA transcripts are found dysregulated.
Monday, September 30, 2013
A coculture system of polarized human endometrial epithelium and subject-paired stroma reveals effects of paracrine signaling on cell-specific global gene expression and cytokine production.
Friday, August 30, 2013
Reflections on "Discovery of biomarkers of endometrial receptivity through a minimally invasive approach: a validation study with implications for assisted reproduction" by Chan et al.
Monday, February 4, 2013
Microarray data revealed altered expression of several novel invasion-associated molecules in leukemia inhibitory factor (LIF)-treated HTR-8/SVneo cells, wherein silencing of pappalysin 1 reduced LIF-mediated invasion.
Friday, May 25, 2012
Characterization of ploidy errors in 274 blastomeres using a novel informatics-based technique revealed aneuploidy profiles with unprecedented detail, including identifying parental origin of aneuploidy and differentiating mitotic from meiotic errors.
Thursday, May 24, 2012
A focused review is presented of the scientific literature pertaining to spermatozoal RNA.
Friday, May 4, 2012
Gene microarray analysis allows comparison of gene expression of adhesion and normal peritoneal tissues. We identified several specific genes with functions relevant to the pathogenesis of postoperative adhesions.