Melatonin and the circadian system Contributions to successful female reproduction

Wednesday, July 30, 2014
Both circadian rhythms and melatonin are important for optimal function of the peripheral reproductive system. In addition to synchronizing rhythms, melatonin may protect the ovary, especially the oocyte and the placenta, from oxidative damage.

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Clinical significance of melatonin receptors in the human myometrium

Wednesday, July 30, 2014
Melatonin receptor expression is upregulated in the pregnant human myometrium at the time of labor, leading to synergism with oxytocin signaling to promote high uterine contractility and parturition at night.

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Spectral modulation of light wavelengths using optical filters Effect on melatonin secretion

Wednesday, July 30, 2014
We describe the potential use of optical filters that block light wavelengths below 480 nm as an effective method to prevent acute disruption in circadian rhythm phase markers, including suppression of melatonin by light exposure at night.

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Melatonin influences on steroidoigenic gene expression in the ovary of pinealectomized rats

Wednesday, June 25, 2014
Because Cyp17a1 expression level was increased in the theca interna and interstitial cells in pinealectomized rats receiving vehicle, melatonin may influence CYP17A1 expression and steroidogenesis in the ovaries.

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Melatonin supplementation during controlled ovarian stimulation for women undergoing assisted reproductive technology Systematic review and meta analysis of randomized controlled trials

Tuesday, December 31, 2013
More studies investigating the role of melatonin supplementation during controlled ovarian stimulation for improving assisted reproductive technology outcomes are still needed before recommending its use in clinical practice.

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