Imaging and angiography in male factor infertility

Wednesday, June 1, 2016
Ultrasound imaging and angiography techniques play a crucial role in the diagnosis and treatment of men with subfertility.

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Limitations and barriers in access to care for male factor infertility

Sunday, May 1, 2016
Male infertility is underrepresented as a disease. Acknowledging and addressing the barriers in access to care for male infertility is necessary for improving reproductive care and outcomes in the United States.

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The relationship between paternal somatic health and assisted reproductive technology outcomes

Monday, April 25, 2016

Authors:
Michael L. Eisenberg, M.D., Shufeng Li, B.S., Lauren A.…

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CYP1A1 3801T C polymorphism implicated in altered xenobiotic metabolism is not associated with variations in sperm production and function as measured by total motile sperm and fertilization rates with intracytoplasmic sperm injection

Monday, April 4, 2016

Authors:
Jason M. Franasiak, M.D., Rebecca Barnett, M.D., Thomas A.…

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Increased risk of incident chronic medical conditions in infertile men Analysis of United States claims data

Tuesday, March 1, 2016
Men diagnosed with male factor infertility had a significantly higher risk of adverse health outcomes in the years after an infertility evaluation.

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Claims-based analysis of male infertility A cautious step in the right direction

Tuesday, March 1, 2016

Authors:
Anthony J. Schaeffer, M.D., M.P.H., James M.…

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Sperm DNA fragmentation and mitochondrial membrane potential combined are better for predicting natural conception than standard sperm parameters

Tuesday, March 1, 2016
Sperm DNA fragmentation and mitochondrial membrane potential combined are superior to standard sperm parameters in predicting natural conception.

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Male fertility preservation Innovations and questions

Monday, February 1, 2016
A protocol for cryopreservation of human endometrial epithelial cells allows for successful recovery and establishment of functional characteristics.

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Experimental methods to preserve male fertility and treat male factor infertility

Monday, February 1, 2016
This article describes experimental stem cell and gene therapies that might be used to treat male factor infertility.

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Decreased fecundity and sperm DNA methylation patterns

Tuesday, December 29, 2015
Sperm DNA methylation profiles at five distinct genomic regions are associated with decreased fecundity in a well-characterized patient population.

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Spontaneous fertility and IVF outcome The new evidence of HPV sperm infection

Tuesday, December 29, 2015
This clinical study demonstrates a significant association between HPV sperm infection, reduced pregnancy rates, and higher miscarriage rates in couples undergoing assisted reproduction.

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Global deoxyribonucleic acid methylation A window into the spermatogonial stem cells reproductive potential

Monday, November 30, 2015

Author:
Jim Hotaling, M.D., M.S., F.E.C.S.M.…

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Evaluating γH2AX in spermatozoa from male infertility patients

Tuesday, September 1, 2015
γH2AX might be a useful biomarker for evaluating double-stranded breaks in human spermatozoa.

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Relationship of paternal age with outcome of percutaneous epididymal sperm aspiration intracytoplasmic sperm injection in cases of congenital bilateral absence of the vas deferens

Tuesday, September 1, 2015
In cases of congenital bilateral absence of the vas deferens, advanced paternal age has a negative effect on retrieved-sperm parameters.

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Whole exome sequencing identifies novel homozygous mutation in NPAS2 in family with nonobstructive azoospermia

Thursday, July 30, 2015
Whole exome sequencing identified homozygous mutation in NPAS2 in a family of men with nonobstructive azoospermia.

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Subspecialty training in andrology

Monday, June 29, 2015
The historical development and current status of andrology fellowship training in Europe and the United States are considered, with an eye toward the future of andrology training in both of those regions.

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Mutational screening of NR5A1 gene encoding steroidogenic factor 1 SF 1 in cryptorchidism and male factor infertility and functional analysis of seven undescribed mutations

Monday, June 29, 2015
This study shows that NR5A1 mutations are a novel cause of severe primary spermatogenic impairment and suggests that isolated cryptorchidism might be another phenotype associated with disruption of NR5A1-mediated pathways.

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Relationship between physical occupational exposures and health on semen quality Data from the Longitudinal Investigation of Fertility and the Environment LIFE Study

Wednesday, April 29, 2015
Occupational and medical comorbidity may negatively impact semen quality.

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Fluorescence in situ hybridization detects increased sperm aneuploidy in men with recurrent pregnancy loss

Monday, March 30, 2015
Men with recurrent pregnancy loss and normal semen parameters exhibit increased sperm aneuploidy detected by fluorescence in situ hybridization.

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Spontaneous pregnancy rates in Chinese men undergoing microsurgical subinguinal varicocelectomy and possible preoperative factors affecting the outcomes

Friday, February 27, 2015
Microsurgical varicocelectomy could improve semen quality and spontaneous pregnancy rates in patients with varicoceles. Patients with high initial sperm concentration may benefit from varicocelectomy.

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Dietary fatty acid intakes and asthenozoospermia A case control study

Monday, December 29, 2014
The high intake of saturated and trans-fats was positively related to asthenozoospermia. Dietary omega-3 polyunsaturated fatty acids are dose dependently and inversely associated with reduced odds of asthenozoospermia.

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Relationship between semen production and medical comorbidity

Monday, December 29, 2014
Men with medical comorbidities have a higher rate of abnormal semen parameters.

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Fluorescent in situ hybridization of human sperm Diagnostics indications and therapeutic implications

Tuesday, November 25, 2014
This article presents a review of the diagnostic and therapeutic indications of sperm fluorescent in situ hybridization and how its use affects treatment of patients with infertility and unfavorable pregnancy outcomes.

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Male infertility testing Reactive oxygen species and antioxidant capacity

Tuesday, November 25, 2014
Elevated reactive oxygen species (ROS) levels have been associated with abnormal semen parameters and male infertility. The impact ofROSon fertilization rates and pregnancy remains controversial.

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Reactive oxygen species in human semen Validation and qualification of a chemiluminescence assay

Tuesday, November 25, 2014
Reactive oxygen species can be measured accurately and reliably with the use of a simple luminol- based chemiluminescence assay. This test can be incorporated into routine testing of human semen for male infertility.

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Sperm functional tests

Tuesday, November 25, 2014
Sperm functional assays are highly predictive of in vitro fertilization/intracytoplasmic sperm injection outcome results and have the potential to assist in clinical decision making, especially to avoid the current long-standing treatment with intrauterine insemination.

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Hepatitis B virus infection and the risk of male infertility A population based analysis

Tuesday, November 25, 2014
This population-based study demonstrated a significantly increased risk of developing male infertility among HBV carriers (hazard ratio 1.52).

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Temporal and geospatial trends in male factor infertility with assisted reproductive technology in the United States from 1999 2010

Wednesday, July 30, 2014
This study estimates the prevalence and temporal trends of male factor infertility diagnoses within ART clinics in the United States from 1999–2010, and maps the geographic distribution.

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Microdissection testicular sperm extraction in men with Sertoli cell only testicular histology

Wednesday, July 23, 2014
Diagnostic testis biopsy in nonobstructive azoospermia has little value, even when uniform Sertoli cell–only pattern is seen. When both testis volume and follicle-stimulating hormone are considered, sperm retrieval rates are 7%–45%.

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In every end there is a beginning Telomeres in male reproduction

Monday, July 14, 2014
Reflections on "Telomere homeostasis is compromised in spermatocytes from patients with idiopathic infertility" by Reig-Viader et al.

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