Reflections on “Antimüllerian hormone in GnRH antagonist cycles: Prediction of ovarian response and cumulative treatment outcome in good-prognosis patients” by Arce et al.
Both female and male body mass indices (BMI) is important for the outcome of in vitro fertilization/intracytoplasmic sperm injection treatments. Increased female and male BMIs negatively affect the chance of live birth, especially after IVF.
The number of supernumerary vitrified blastocysts correlates positively with the odds of implantation and live birth in single-blastocyst transfers.
AMH predicts oocyte yield and poor and excessive ovarian response in GnRH antagonist cycles and is associated with increased cumulative live-birth rates after single-blastocyst transfer in fresh and cryopreserved cycles.
Trophectoderm grading, but not inner cell mass grading, significantly correlates with implantation and live birth for single-embryo transfers.
A live birth was obtained after frozen/thawed ovarian tissue autologous transplantation in a patient with precocious ovarian failure after chemotherapy and bone marrow transplantation.
One healthy boy was born after transfer of a blastocyst derived from vitrified-warmed spermatozoa from a patient with nonobstructive azoospermia. The spermatozoa were vitrified with the use of Cryotop and Cell Sleeper.
Female age and blastocyst expansion are associated with live birth in patients undergoing SET. Many other clinical factors including obesity do not appear to affect SET outcome.
Patients with a BMI over 30 have up to 68% lower odds of having a live birth following their first ART cycle.
While AFC and age are predictive of live birth following IVF treatment, AFC demonstrates a stronger positive correlation. This study illustrates post-test probabilities of live birth at individual AFC thresholds.
Thyroid peroxidase antibody does not have prognostic value regarding the outcome of a subsequent pregnancy, and empirical thyroxine therapy in those who tested positive did not seem to improve outcome.
Live birth pregnancies are a realistic possibility after administration of a rescue course of hCG and repeat oocyte retrieval in the setting of false empty follicle syndrome.
Gene expression of human cumulus cells is a promising tool to predict oocyte quality in intracytoplasmic sperm injection patients. This retrospective study pinpointed CAMK1D and EFNB2 as strong genes to predict pregnancy outcome.
Couples in which female partners drank coffee, tea, or alcoholic beverages in the past had higher pregnancy and live birth rates compared with never users or current users.
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