Fertility & Sterility Discussion ForumsLetrozole increases ovarian growth and CYP17A1 gene expression
Friday, March 1, 2013
Letrozole increases ovarian size and androgen production and upregulates Cyp17a1 messenger RNA expression in the rat ovary.
Aromatase Inhibitors for the Treatment of Endometriosis
Thursday, November 29, 2012
A review is presented of the role of aromatase in the pathogenesis of endometriosis, discuss the pharmacology of aromatase inhibitors, and examine clinical applications of aromatase inhibitors for endometriosis treatment.
Ovarian stimulation and fertility preservation using aromatase inhibitors in women with breast cancer
Thursday, November 29, 2012
Studies suggest that in the short term, an aromatase inhibitor plus gonadotropin protocol is effective for safely inducing controlled ovarian hyperstimulation in women with breast cancer for fertility preservation.
Does Higher Starting Dose of FSH Stimulation with Letrozole Improve Fertility Preservation Outcomes in Women with Breast Cancer
Thursday, September 27, 2012
Higher FSH start dose does not improve cycle outcomes in women with breast cancer undergoing fertility preservation with letrozole for embryo cryopreservation.
Effect of letrozole on estradiol production and P450 aromatase mRNA expression of cultured luteinized granulosa cells from women with and without endometriosis
Thursday, June 7, 2012
Lower estradiol production and P450 aromatase messenger RNA expression of cultured granulosa cells were found in women with endometriosis, but letrozole in the conditioned media further reduced these parameters.
Changes in the hormonal profile and seminal parameters with the use of aromatase inhibitors in the management of infertile men with low testosterone to estradiol ratios
Wednesday, June 6, 2012
Therapy with 2.5 mg letrozole or 1 mg anastrazole daily, in cases of infertile men with low T/E2 ratios, leads to a significant increase of T/E2 ratio, ejaculate volume, sperm motility, and total motile sperm count.
What is the optimal follicular size before triggering ovulation in intrauterine insemination cycles with clomiphene citrate or letrozole? An analysis of 988 cycles
Friday, May 4, 2012
The optimal size of the leading follicle in cycles with clomiphene citrate and letrozole is in the range of 23–28 mm and is closely related to the endometrial thickness.
Circulating antimüllerian hormone levels in boys decline during early puberty and correlate with inhibin B
Friday, May 4, 2012
This report describes the peripheral levels of inhibin B and antimullerian hormone in boys during peripuberty and in patients with congenital hypogonadotropic hypogonadism.