Sunday, May 1, 2016
In polycystic ovary syndrome (PCOS), higher PDCD4 expression promotes obesity, insulin resistance, lipid metabolism disorders, and induced granulosa cell apoptosis, which is an independent risk factor for PCOS.
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Monday, February 1, 2016
Vigorous exercise is associated with superior health profiles and reduced odds of metabolic syndrome in polycystic ovary syndrome, independent of age, body mass index, or total exercise expenditure.
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Monday, November 30, 2015
In normally cycling premenopausal women, SHBG concentrations, independently from other parameters, are negatively associated with bioavailable T and positively associated with adiponectin.
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Tuesday, September 1, 2015
Insulin resistance was found to be linked to depression risk, after controlling for potential confounders, in women who have polycystic ovary syndrome.
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Friday, February 27, 2015
The presence of adrenal hyperandrogenism in women with polycystic ovary syndrome is associated with reduced insulin sensitivity and increased blood pressure, but may have a beneficial impact on the lipid profile.
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Friday, February 27, 2015
This review explores the off-label use of medications used to manage aspects of polycystic ovary syndrome, including androgen excess, irregular menses, and metabolic changes.
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Tuesday, November 25, 2014
High follicular fluid leptin levels were associated with a lower probability of live birth in women undergoing in vitro fertilization–intracytoplasmic sperm injection. Serum progesterone, follicle number, and leptin levels seem to predict IVF outcome.
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Wednesday, July 30, 2014
The ability of murine ovarian hormone synthesis became abnormal and the ovarian tissue behaved insulin resistance, after treated with dexamethasone, in vivo and in vitro; the Chinese herbal extract cryptotanshinone was found to partially antagonize their behavior.
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Wednesday, June 25, 2014
In primary prevention practice, HOMA-M120 and Sib (Avignon et al.) seem to adequately replace the euglycemic-hyperinsulinemic clamp in lean and overweight/obese PCOS patients, respectively.
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Tuesday, June 17, 2014
The strong correlation of insulin resistance and oxidative stress at the visceral adipose tissue level suggests that local oxidative stress and abnormalities of insulin signaling in the adipose tissue play critical roles in polycystic ovary syndrome insulin resistance.
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Sunday, June 1, 2014
In a randomized, placebo-controlled trial of vitamin D in PCOS, insulin sensitivity was unchanged, but there was a trend toward decreased 2-hour insulin and a protective effect on blood pressure.
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Tuesday, May 20, 2014
Normal weight adolescents with PCOS and a maternal history of PCOS had a significantly increased rate of insulin resistance independent of body mass index and inversely correlated with high molecular weight adiponectin.
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Thursday, February 20, 2014
Patients with type 2 deiodinase (D2) Ala92Ala genotype, associated with an increased risk for diabetes, have decreased placental D2 activity that is not associated with dysglycemia or adverse gestational outcomes.
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Tuesday, December 31, 2013
Baseline characteristics from 750 women with PCOS and their male partners from a multicenter trial show the groups to be well matched with body mass index exacerbating metabolic and reproductive parameters.
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Monday, September 30, 2013
Dietary glycemic index is increased in the classic polycystic ovary syndrome (PCOS) phenotype and associated with less favorable anthropometric and metabolic profiles. Obesity and classic PCOS phenotype are predictors of higher dietary glycemic index.
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Friday, June 28, 2013
Functional magnetic resonance imaging of limbic activation with emotional processing differed between healthy women and women with insulinresistant polycystic ovary syndrome.
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Friday, June 28, 2013
In utero testosterone excess, together with gestational hyperglycemia, may contribute to ontogeny of polycystic ovary syndrome (PCOS). Lifestyle or therapeutic intervention during pregnancy or childhood may alleviate familial genetic predisposition to PCOS.
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Monday, February 4, 2013
Young women with polycystic ovary syndrome and subclinical hypothyroidism present higher serum levels of low-density lipoprotein cholesterol with no changes in other lipid profile parameters, insulin resistance, or phenotypic manifestations.
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Thursday, November 29, 2012
Girls at risk for PCOS are mainly characterized by insulin resistance and resistance to insulin-induced lipolysis suppression. Predisposition to PCOS may thus be related to adipocyte dysfunction.
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Thursday, June 7, 2012
In a cross-sectional study of women with and without polycystic ovary syndrome (PCOS), obesity but not PCOS affected the expression of adipose expression and plasma levels of adipocytokines.
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Thursday, June 7, 2012
Serum 25-hydroxyvitamin D levels are positively correlated with serum antim€ullerian hormone levels in latereproductive-aged women (40 years old).
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Thursday, May 31, 2012
The third polycystic ovary syndrome (PCOS) consensus report summarizes current knowledge and identifies knowledge gaps regarding various women’s health aspects of PCOS.
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Thursday, May 31, 2012
Insulin resistance of variable severity is commonly present in women with PCOS. Arguments and rationale are presented for treating all or only selected women with insulin sensitizing drugs.
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Thursday, May 31, 2012
We studied the effect of acupuncture and exercise on hemostatic factors, insulin sensitivity, and adipose tissue characteristics in PCOS. Acupuncture counteracted a possible prothrombotic state in women with PCOS as reflected by decreased plasminogen activator inhibitor activity.
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Thursday, May 31, 2012
In women with PCOS, hyperandrogenemia appears to diminish during reproductive life whereas insulin resistance persists. This progressive worsening of insulin resistance is primarily driven by the increase in obesity.
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Thursday, May 24, 2012
The increased risk for obstructive sleep apnea (OSA) in PCOS may be related to obesity. Nonobese women with PCOS are not at increased risk for OSA compared with control women with similar body mass indexes.
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Friday, May 11, 2012
Adolescents with PCOS had higher intrahepatic lipid content and a statistical trend for higher retinol-binding protein 4 (RBP4) levels than controls. There may be an independent relationship between RBP4 and triglycerides.
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Fertility Sterility Discussion