Small follicles may be a promising source of oocytes in modified natural cycle in vitro fertilization embryo transfer

Tuesday, March 15, 2016

Author:
Zeev Blumenfeld, M.D.…

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Live birth following in vitro maturation of oocytes retrieved from extracorporeal ovarian tissue aspiration and embryo cryopreservation for 5 years

Thursday, October 29, 2015
Extracorporeal aspiration of immature oocytes from ovarian tissue, in vitro maturation, embryo cryopreservation, and a delayed frozen embryo transfer ultimately led to a live birth.

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In vitro maturation of oocytes is not associated with altered deoxyribonucleic acid methylation patterns in children from in vitro fertilization or intracytoplasmic sperm injection

Friday, February 27, 2015
Methylation analysis of 15 developmentally important genes and 2 repeats in 11 IVM children and 19 controls did not provide evidence for IVM-induced epigenetic changes.

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Prolonging oocyte in vitro culture and handling time does not compensate for a shorter interval from human chorionic gonadotropin administration to oocyte pickup

Monday, December 29, 2014
Delaying oocyte denudation or injection does not compensate for a suboptimal in vivo exposure to the follicular environment.

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Comparison of complication rates and pain scores after transvaginal ultrasound guided oocyte pickup procedures for in vitro maturation and in vitro fertilization cycles

Thursday, February 20, 2014
Complication types and rates seem similar after transvaginal ultrasound–guided oocyte collection in in vitro maturation and conventionally stimulated in vitro fertilization cycles.

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A freeze all embryo strategy after in vitro maturation a novel approach in women with polycystic ovary syndrome

Monday, September 30, 2013
In vitro maturation (IVM) of oocytes followed by a “freeze-all” embryo strategy results in promising clinical outcomes in patients with polycystic ovary syndrome and circumvents the potential problem of suboptimal endometrial quality in IVM cycles.

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Fertilization and embryo development with spermatozoa obtained from testicular sperm extraction into oocytes generated from human chorionic gonadotropin primed in vitro maturation cycles

Monday, September 30, 2013
The fertilization rate and embryo development of IVM oocytes after intracytoplasmic sperm injection (ICSI) using testicular spermatozoa was lower than that of sibling in vivo-matured oocytes.

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Estrogen suppressed in vitro maturation A novel approach to in vitro maturation

Friday, May 31, 2013
Estrogen-suppressed in vitro maturation eliminates the need for gonadotropin stimulation and cycle monitoring yet results in a 40% live-birth rate.

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In vitro maturation of oocytes Uncommon indications

Thursday, March 28, 2013
In vitro maturation may be an attractive option in patients suffering from ovarian resistance to FSH and for preserving fertility in combination with ovarian tissue cryopreservation.

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Optimizing human oocyte cryopreservation for fertility preservation patients Should we mature then freeze or freeze then mature

Thursday, March 28, 2013
Germinal vesicle and metaphase I oocytes should be matured in vitro before cryopreservation to optimize the reproductive potential of all retrieved oocytes.

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In vitro maturation remains an interesting procedure

Thursday, March 28, 2013
A discussion is presented concerning the health of IVM infants.

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Oocyte in vitro maturation in normo ovulatory women

Thursday, March 28, 2013
In normo-ovulatory women, in vitro maturation does not result in success rates similar to conventional ovarian stimulation regimens. However, it represents a milder approach to assisted reproduction treatment and an alternative intervention for specific conditions.

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New approach in patients with polycystic ovaries lessons for everyone

Thursday, March 28, 2013
In vitro maturation, including FSH priming, recovery of oocytes from 12-mm follicles, and using single blastocyst transfer, is safe and provides pregnancy rates up to 40% in patients with PCO.

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The dynamics of in vitro maturation of germinal vesicle oocytes

Thursday, November 1, 2012
Immature germinal vesicle oocytes recovered from stimulated cycles were spontaneously matured in vitro. Using real-time technology, the dynamics of nuclear maturation were studied and the most favorable duration of MII arrest (i.e., that corresponding with the highest number of matured oocytes displaying a normal activation response) was determined.

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Retrieving oocytes from small non-stimulated follicles in polycystic ovary syndrome(PCOS): in vitro maturation (IVM) is not indicated in the new GnRH antagonist era

Friday, June 22, 2012
By effectively preventing OHSS, the antagonist protocol with GnRH-a trigger is a better option for treating women with PCOS than in vitro maturation (IVM).

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Developmental capacity of in vitro-matured human oocytes retrieved from polycystic ovary syndrome ovaries containing no follicles larger than 6 mm

Friday, June 8, 2012
Contrary to earlier belief, immature oocytes retrieved from small antral follicles with a diameter of <6 mm in patients with polycystic ovaries or polycystic ovary syndrome exhibit significant growth in vitro and can acquire oocyte developmental competence, support embryo development, and develop into healthy offspring.

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Strain-specific spontaneous activation during mouse oocyte maturation

Thursday, June 7, 2012
Oocyte spontaneous activation, an irregularity of the cell cycle that can lead to ovarian teratomas, has genetic variation among inbred mouse strains, and is sensitive to the culture environment.

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Insufficient histone-3 lysine-9 deacetylation in human oocytes matured in vitro is associated with aberrant meiosis

Friday, June 1, 2012
The increased incidence of aberrant meiosis in in vitro–matured human oocytes correlates with persistence of lysine-9 acetylation of histone-3.

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