Selection of high potential embryos using time lapse imaging The era of morphokinetics

Monday, March 18, 2013
Time-lapse is a promising tool with the potential to revolutionize embryology and IVF success rates. It provides an uninterrupted information flow on embryo development not otherwise available through standard evaluation.

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Neohormones as Biomarkers of Reproductive Health

Monday, March 18, 2013
The relaxin family of peptide hormones and their receptors represent typical neohormone systems involved in mammalian-specific aspects of male and female reproduction and thus are ideal biomarkers of reproductive health.

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Blastocyst culture and transfer in clinical assisted reproduction

Friday, March 1, 2013
Blastocyst embryo transfer improves the live-birth rate in good prognosis patients compared with cleavage-stage transfer. In unselected or poor prognosis patients, it is not proven superior to cleavage-stage transfer.

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The effect of delayed initiation of gonadotropin releasing hormone antagonist in a flexible protocol on in vitro fertilization outcome

Friday, March 1, 2013
Delayed administration of GnRH antagonist in a flexible protocol is associated with an attenuated pattern of ovarian response to stimulation but has no effect on implantation and pregnancy rates.

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Limited Implantation Success of Direct Cleaved Human Zygotes A Time Lapse Study

Thursday, November 29, 2012
In a multicenter retrospective study, embryos with direct cleavage from two to three cells (5 hours) had a statistically significantly lower implantation rate than embryos with a normal cleavage pattern.

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Pinopodes, Leukemia Inhibitory Factor, Integrin-β3, and Mucin-1 Expression in the Peri-implantation Endometrium of Women with Unexplained Recurrent Pregnancy Loss

Friday, June 8, 2012
Mucin-1 expression is lower in peri-implantation endometrium of women with recurrent pregnancy loss than in controls, but pinopode morphology and coverage, and leukemia inhibitory factor and integrin-b3 expression are similar.

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Expression and activation of the membrane-cytoskeleton protein ezrin during the normal endometrial cycle

Monday, June 4, 2012
Ezrin/phospho-ezrin immunoreactivity are present on apical surfaces of the luminal epithelium, around secretory vacuoles and in luminal secretions during the secretory phase. These findings have functional implications for implantation biology.

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Developmental potential of embryos from intracytoplasmic sperm injection cycles containing fragmented oocytes

Friday, May 25, 2012
Fragmented oocytes occur rarely in intracytoplasmic sperm injection cycles, but their presence is associated with reduced developmental potential of sibling oocytes and lower implantation and pregnancy rates.

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A high-throughput in vitro model of human embryo attachment

Friday, May 11, 2012
A high-throughput attachment model involving coculture of human endometrial epithelial cells and fluorescence-labeled trophoblast spheroids was established and validated.

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Repeated implantation failure: clinical approach

Friday, May 4, 2012
Repeated implantation failure should be assessed for different causes and treated accordingly.

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Why does the fallopian tube fail in ectopic pregnancy? The role of activins, inducible nitric oxide synthase, and MUC1 in ectopic implantation

Friday, May 4, 2012
The pathologic expression of candidate molecules by tubes bearing an ectopic pregnancy does not determine the implantation site, but they may be involved in regulation of the trophoblast.

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Defective endometrial receptivity

Friday, May 4, 2012
Defective endometrial receptivity is secondary to intrauterine pathology or aberrant development of adhesive properties at the molecular level. Investigation and treatment of endometrial pathology will increase IVF success rates.

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