Although the controlled ovarian stimulation protocol with short GnRH agonist in alternate days may lower the cost of an individual IVF cycle, it requires more cycles to achieve pregnancy.
Our group experience demonstrates a clinical advantage for IMSI procedure in patients who failed in their first ICSI or for patients who shifted between ICSI and IMSI modalities.
This review examines new techniques that are designed to prepare a clean “normal” sperm population or that assist in selecting an individual “normal” spermatozoon.
Density gradient and washing can remove HCV RNA or HIV RNA from microsurgical epididymal sperm aspiration or testicular sperm extraction samples obtained from HCV- or HIV-infected azoospermic men before ICSI.
There is solid evidence that Beckwith-Wiedemann syndrome is significantly positively associated with IVF or ICSI. There is no proof for a causal relationship between imprinted diseases and ART.
We found that in oligozoospermic male intracytoplasmic sperm injection candidates, the abnormal karyotype rate was <2%. The small risk of conceiving a child with unbalanced structural chromosomal abnormalities may not justify karyotyping these men.
This committee opinion assesses the literature, where available, to identify situations where intracytoplasmic sperm injection may be indicated in the absence of an identified male factor.
Pregnancies arising from the transfer of frozen thawed IVF embryos have better obstetric and perinatal outcomes based on the observational data.
Polyvinylpyrrolidone-based medium can induce sperm DNA fragmentation during intracytoplasmic sperm injection, and frozen-thawed sperm from oligozoospermic ejaculates are more susceptible to in situ DNA fragmentation.
Human oocytes can be infected with HIV via ICSI when high amounts of virus are injected, but the chances that an infection will occur in a clinical setting are less than 0.00002%.
The examination of 66 in vitro fertilization–conceived children and 69 control children revealed no imprinting abnormalities at H19, KCNQ1OT1, SNRPN, or IGF2. Satellite 2 methylation was normal, and no global changes in methylation were detected.
Intracytoplasmic sperm injection is the most effective and safe treatment in case of partial globozoospermia, although spontaneous pregnancies do occur in this population.
Children conceived by IVF and/or ICSI are at significantly increased risk for birth defects, and there is no risk difference between IVF children and ICSI children.
Fragmented oocytes occur rarely in intracytoplasmic sperm injection cycles, but their presence is associated with reduced developmental potential of sibling oocytes and lower implantation and pregnancy rates.
We describe the early steps that brought forth the development of intracytoplasmic sperm injection and its role in assisted reproduction techniques.
We describe the early steps that brought about the establishment of assisted fertilization techniques culminating in intracytoplasmic sperm injection (ICSI) along with presentations of current diagnostic screening methods for spermatozoal (dys)function.
Retrospective cohort analysis of 4,202 births resulting from blastocyst versus nonblastocyst transfer demonstrated no significant difference in maternal and perinatal outcomes, although blastocyst transfer may increase preeclampsia and placenta previa.
Sheep oocyte quality was assessed by brilliant cresyl blue (BCB) staining. Stained oocytes (BCB+) showed more adenosine triphosphate and more blastocysts after IVF than BCB. Differences in blastocyst percentages were not observed after ICSI.
We present a meta-analysis evaluating the safety and efficacy of corifollitropin alfa administration in women undergoing controlled ovarian stimulation in GnRH antagonist down-regulated IVF/ICSI treatment cycles.
We present oocyte slow-freezing outcomes using a differential sucrose concentration during dehydration (0.2 M) and rehydration (0.3 M).
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