Digital multiplexed mRNA analysis of functionally important genes in single human oocytes and correlation of changes in transcript levels with oocyte protein expression

Thursday, February 20, 2014
Measurement of transcript levels in single human oocytes with the use of Nanostring and correlation with protein expression identified biologically meaningful oocyte-to-oocyte heterogeneity in functionally important regulatory pathways.

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A new approach to evaluate aging effects on human oocytes Fourier transform infrared imaging spectroscopy study

Tuesday, December 31, 2013
By using Focal Plane Array Fourier transform infrared spectroscopy, evidence of damage from aging on human oocytes was pinpointed in the composition and distribution of the principal biocomponents (proteins, lipids, carbohydrates, and nucleic acids).

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Ovarian follicle culture advances and challenges for human and nonhuman primates

Tuesday, April 30, 2013
Recent progress in developing human and nonhuman primate follicle culture systems with the goal of obtaining competent oocytes is reviewed, and prospects for clinical application for fertility preservation are discussed.

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Expression of survivin in human oocytes and preimplantation embryos

Monday, February 4, 2013
The study demonstrated that a specific survivin mRNA and protein are expressed in human oocytes and embryos. Embryos secrete survivin into culture media, and survivin concentrations are positively correlated with embryo cleavage rates.

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