Association of the very early rise of human chorionic gonadotropin with adverse outcomes in singleton pregnancies after in vitro fertilization

Sunday, May 1, 2016
Slower very early first-trimester human chorionic gonadotropin rise is associated with low birth weight but not gestational age at delivery among singleton in vitro fertilization conceptions.

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Growth trend of small uterine fibroids and human chorionic gonadotropin serum levels in early pregnancy An observational study

Sunday, May 1, 2016
Small fibroids seem to grow rapidly in the first weeks of pregnancy, with a nonlinear trend, in relation to the similar growth of human chorionic gonadotropin in the same period.

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Major drawbacks and additional benefits of agonist trigger Not ovarian hyperstimulation syndrome related

Monday, March 30, 2015
High responders and oocyte donors may now be stimulated and triggered with reasonable safety. This paradigm shift confers certain advantages and potential new risks.

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Prolonging oocyte in vitro culture and handling time does not compensate for a shorter interval from human chorionic gonadotropin administration to oocyte pickup

Monday, December 29, 2014
Delaying oocyte denudation or injection does not compensate for a suboptimal in vivo exposure to the follicular environment.

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Endometrial infusion of human chorionic gonadotropin at the time of blastocyst embryo transfer does not impact clinical outcomes A randomized double blind placebo controlled trial

Tuesday, November 25, 2014
This randomized double-blinded placebo-controlled trial of 300 patients undergoing fresh or frozen embryo transfer (ET) demonstrates that endometrial human chorionic gonadotropin infusion at the time of blastocyst ET does not improve sustained implantation rate.

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Human chorionic gonadotropin versus gonadotropin releasing hormone agonist trigger in assisted reproductive technology The king is dead long live the king

Wednesday, July 30, 2014
In this Conceptions piece, we set out to explore whether current scientific evidence supports the future use of a GnRH-a trigger in all IVF patients co-treated with a GnRH antagonist, regardless of ovarian response on the day of trigger.

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Lag time from ovulation trigger to oocyte aspiration and oocyte maturity in assisted reproductive technology cycles A retrospective study

Wednesday, July 30, 2014
The proportion of metaphase II oocytes increases up to a 35-hour lag time between oocytematuration trigger and aspiration and then stabilizes up to 38 hours.

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Interleukin 25 induced by human chorionic gonadotrophin promotes the proliferation of decidual stromal cells by activation of JNK and AKT signal pathways

Wednesday, June 25, 2014
Interleukin-25 expression was enhanced by trophoblast-derived hCG, could stimulate the proliferation of DSCs through activating JNK and AKT signals, which finally contributes to the establishment and maintenance of physiological pregnancy.

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Human chorionic gonadotropin discriminatory zone in ectopic pregnancy Does assay harmonization matter

Sunday, June 1, 2014
Despite significant differences in human chorionic gonadotropin (hCG) concentrations across hCG immunoassays, an hCG discriminatory zone of 1,500–3,500 IU/L can be used for all but one commonly used hCG reagent platform.

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Preventing ovarian hyperstimulation with gonadotropin releasing hormone agonist trigger Is anything perfect

Monday, March 31, 2014
Reflections on "Severe ovarian hyperstimulation syndrome after gonadotropin-releasing hormone (GnRH) agonist trigger and “freeze-all” approach in GnRH antagonist protocol" by Fatemi et al.

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Hyperglycosylated human chorionic gonadotropin as an early predictor of pregnancy outcomes after in vitro fertilization

Friday, January 31, 2014
Hyperglycosylated human chorionic gonadotropin (hCG) measured as early as 9 days after egg retrieval is superior to traditional hCG and highly predictive of ongoing pregnancies after fresh IVF–embryo transfer.

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Decreased inhibin B responses following recombinant human chorionic gonadotropin administration in normal women and women with polycystic ovary syndrome

Tuesday, December 31, 2013
In normal and polycystic ovary syndrome (PCOS) women, inhibin B production was decreased following recombinant hCG administration. These findings suggest that in PCOS women, androgen excess is not enhanced by LH-stimulated inhibin B production.

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Early luteal phase endocrine profile is affected by the mode of triggering final oocyte maturation and the luteal phase support used in recombinant FSH GnRH antagonist IVF cycles

Friday, August 30, 2013
In oocyte donors triggered with a bolus of GnRHa, gonadotropin and steroid levels during the early luteal phase differed significantly according to the type of luteal phase support used after triggering.

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Pituitary Origin of Persistently Elevated Human Chorionic Gonadotropin in a Patient with Gonadal Failure

Wednesday, January 2, 2013
Pituitary hCG should be considered in the differential diagnosis of persistently elevated hCG levels in young patients with gonadal failure when the more common and more ominous causes have been excluded.

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Epithelial cell protein milk fat globule epidermal growth factor 8 and human chorionic gonadotropin regulate stromal cell apoptosis in the human endometrium

Thursday, November 29, 2012
Milk fat globule–epidermal growth factor 8, a multifunctional epithelial protein in the human endometrium, and hCG modulate apoptosis of stromal cells.

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Maternal body mass index and serum concentrations of human chorionic gonadotropin in very early pregnancy

Thursday, September 27, 2012
High maternal BMI was associated with low serum hCG concentrations on day 16 after ovulation induction in 2,110 singleton and in 516 multiple pregnancies after ART.

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Can in vitro fertilization cycles be salvaged by repeat administration of intramuscular human chorionic gonadotropin the day after failed injection?

Friday, June 15, 2012
This study investigated the incidence of failed hCG administration as evidenced by negative serum β-hCG after initial trigger injection, and the ability to salvage such cycles through repeat administration of hCG before retrieval.

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Efficacy and safety of human chorionic gonadotropin for follicular phase stimulation in assisted reproduction: a systematic review and meta-analysis

Wednesday, May 30, 2012
The administration of human chorionic gonadotropin in the early and late follicular phase in controlled ovarian stimulation shows results similar to the conventional regimens, with the advantage of decreasing the doses of follicle-stimulating hormone.

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Agonist trigger: what is the best approach? Agonist trigger and low dose hCG

Tuesday, May 22, 2012
Low-dose hCG supplementation after GnRHa trigger secures the reproductive outcome and minimizes the risk of OHSS in the high-risk IVF patient.

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