Evaluation of ribonucleic acid amplification protocols for human oocyte transcriptome analysis

Monday, February 1, 2016
The authors validated protocols that produce reliable and reproducible gene-expression profiles of individual human oocytes.

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Melatonin influences on steroidoigenic gene expression in the ovary of pinealectomized rats

Wednesday, June 25, 2014
Because Cyp17a1 expression level was increased in the theca interna and interstitial cells in pinealectomized rats receiving vehicle, melatonin may influence CYP17A1 expression and steroidogenesis in the ovaries.

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Diet induced maternal obesity alters ovarian morphology and gene expression in the adult mouse offspring

Wednesday, June 11, 2014
Ovaries of mouse offspring from high–fat–fed obese dams have reduced follicular population and altered gene expression, which could impact their reproductive potential.

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Digital multiplexed mRNA analysis of functionally important genes in single human oocytes and correlation of changes in transcript levels with oocyte protein expression

Thursday, February 20, 2014
Measurement of transcript levels in single human oocytes with the use of Nanostring and correlation with protein expression identified biologically meaningful oocyte-to-oocyte heterogeneity in functionally important regulatory pathways.

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Impact of final oocyte maturation using gonadotropin releasing hormone agonist triggering and different luteal support protocols on endometrial gene expression

Tuesday, December 31, 2013
Genes related to endometrial receptivity were analyzed on 25 endometrial samples after GnRH-a triggering and different luteal support protocols; adding LH/hCG activity more closely resembles the expression after hCG triggering.

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Growth differential factor 9 inhibits testosterone production in mouse theca interstitial cells

Thursday, October 31, 2013
Growth differential factor-9 can inhibit the production of testosterone in mouse theca interstitial cells and suppress corresponding gene expression.

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Gene expression profiles of cumulus cells obtained from women treated with recombinant human luteinizing hormone plus recombinant human follicle stimulating hormone or highly purified human…

Friday, May 31, 2013
Different gonadotropin stimulation regimens and LH source modulate cumulus cell transcriptomes, probably by influencing gonadotropin receptor activity and downstream signaling.

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Immature myeloid cells derived from mouse placentas and malignant tumors demonstrate similar proangiogenic transcriptional signatures

Friday, March 1, 2013
Immature myeloid cells derived from placentas and tumors show similar molecular signatures. This common gene expression pattern may indicate that these cells share the same origins and functions.

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Identification of a novel gene set in human cumulus cells predictive of an oocytes pregnancy potential

Friday, March 1, 2013
This study identified a 12-gene signature in human cumulus cells predictive of pregnancy across multiple clinics. The positive predictive value of our test was 81% with an area under the receiver operating characteristic of 0.763  0.079.

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Clomiphene citrate potentiates the adverse effects of estrogen on rat testis and down regulates the expression of steroidogenic enzyme genes

Wednesday, January 2, 2013
The effects of clomiphene citrate on testicular function and steroidogenic enzyme gene expression were investigated in rats estrogenized with estradiol-3-benzoate.

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New candidate genes to predict pregnancy outcome in single embryo transfer cycles when using cumulus cell gene expression

Thursday, June 7, 2012
Gene expression of human cumulus cells is a promising tool to predict oocyte quality in intracytoplasmic sperm injection patients. This retrospective study pinpointed CAMK1D and EFNB2 as strong genes to predict pregnancy outcome.

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Gene and protein expression signature of endometrial glandular and stromal compartments during the window of implantation

Wednesday, May 30, 2012
A significant biological pathway, the cell cycle,was identified along with signature protein staining patterns after gene expression of the receptive endometrium was determined via laser microdissected glands and stroma.

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Microarray expression profiling in adhesion and normal peritoneal tissues

Friday, May 4, 2012
Gene microarray analysis allows comparison of gene expression of adhesion and normal peritoneal tissues. We identified several specific genes with functions relevant to the pathogenesis of postoperative adhesions.

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