In bag manual versus uncontained power morcellation for laparoscopic myomectomy Randomized controlled trial

Sunday, May 1, 2016
Protected manual in-bag morcellation may be considered efficient and feasible in that it does not interfere with surgical outcomes in women undergoing laparoscopic myomectomy.

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Effect of menses on standardized assessment of sexual dysfunction among women with uterine fibroids A cohort study

Thursday, July 30, 2015
Women with uterine fibroids report differences in specific domains on a validated measure of sexual functioning during menses vs. between menses.

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Techniques for contained morcellation in gynecologic surgery

Monday, March 30, 2015

Original Video Article

Serene S.…

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Tranilast an orally active anti allergic compound inhibits extracellular matrix production in human uterine leiomyoma and myometrial cells

Wednesday, July 30, 2014
Tranilast reduces fibronectin, COL1A1, versican, and activin-A expression in leiomyoma and myometrial cells.

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An engaging example of translational medicine The Wnt β catenin cellular pathway and pharmacological research in fibroid treatment

Wednesday, April 30, 2014
Reflections on "Inhibition of canonical WNT signaling attenuates human leiomyoma cell growth" by Ono et al.

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Effect of fibroids not distorting the endometrial cavity on the outcome of in vitro fertilization treatment A retrospective cohort study

Thursday, February 20, 2014
A retrospective cohort study demonstrates that intramural fibroids with diameter larger than 2.85 cm have a negative effect on in vitro fertilization/intracytoplasmic sperm injection delivery rates.

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Vaginal mifepristone for the treatment of symptomatic uterine leiomyomata An open label study

Friday, January 31, 2014
Vaginal mifepristone may offer an effective treatment option for women with symptomatic uterine leiomyomas and can improve the patients’ quality of life.

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Complex networks of multiple factors in the pathogenesis of uterine leiomyoma

Friday, June 28, 2013
Several factors, such as genetic, epigenetic, steroids, growth factors, cytokines, chemokines, and extracellular matrix components, have been identified in myometrial and leiomyoma biology that are hereby reviewed and discussed.

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A novel mouse model that closely mimics human uterine leiomyomas

Friday, March 1, 2013
Ex vivo expanded myoma cells or transformed and immortalized by SV40ER lose in vivo tumorigenicity. Injections of uncultured primary myoma cells produce stable xenografts with unique similarity to human fibroids.

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New Science Will Move Fibroid Therapies Into the 21st Century

Tuesday, June 12, 2012

Elizabeth A. Stewart, M.D.…

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Adverse obstetric outcomes associated with sonographically identified large uterine fibroids

Friday, June 1, 2012
Women with large uterine fibroids delivered at an earlier gestational age compared to women with small or no fibroids. Blood loss and rate of blood transfusion were also increased.

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