Gonadotropin releasing hormone agonists for the preservation of ovarian function among women with breast cancer who did not use tamoxifen after chemotherapy A systematic review and meta analysis

Tuesday, June 3, 2014
Resumption of menses 1 year or more after treatment is similar among women with breast cancer who receive a gonadotropin-releasing hormone agonist with chemotherapy or chemotherapy alone.

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Ovarian tissue cryopreservation A committee opinion

Wednesday, April 30, 2014
This document describes the strategy of ovarian tissue cryopreservation to preserve fertility in patients who may undergo gonadotoxic medical therapy, radiation therapy, or gonadectomy.

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Eliminating acute lymphoblastic leukemia cells from human testicular cell cultures A pilot study

Monday, March 31, 2014
A testicular cell culture system allows for efficient propagation of spermatogonial stem cells from a biopsy for fertility preservation and also eliminates contaminating malignant acute lymphoblastic leukemia cells.

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The artificial ovary Any new step is a step foward

Monday, March 31, 2014
Reflections on "A new step toward the artificial ovary: survival and proliferation of isolated murine follicles after autologous transplantation in a fibrin scaffold" by Luyckx et al.

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Outcomes of operative sperm retrieval strategies for fertility preservation among males scheduled to undergo cancer treatment

Thursday, February 20, 2014
Electroejaculation and testicular sperm extraction led to successful sperm retrieval in 60% of adolescents and teenagers and 59% of adult men seeking fertility preservation before cancer therapy.

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Neoadjuvant intraarterial chemotherapy followed by total laparoscopic radical trachelectomy in stage IB1 cervical cancer

Thursday, February 20, 2014
Neoadjuvant intra-arterial chemotherapy followed by total LRT may become a useful option for women with cervical cancer with a tumor size larger than 2 cm who wish to preserve fertility.

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Improving ovarian tissue cryopreservation for oncologic patients Slow freezing versus vitrification effect of different procedures and devices

Thursday, February 20, 2014
Vitrification of ovarian tissue employing ethylene glycol and dimethyl sulfoxide in metallic grids preserves morphology of follicles and stroma, and maintains proliferation, viability, and vascularization status similarly to fresh tissue.

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In search of signaling pathways critical for ovarian graft reception Akt1 is essential for long term survival of ovarian grafts

Friday, January 31, 2014
Akt1 has a critical role in ovarian graft reception: although ovarian grafts lacking Akt1 activity survive the immediate posttransplantation period, long-term survival of the graft is impaired.

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Germline stem cells Toward the regeneration of spermatogenesis

Tuesday, December 31, 2013
Stem cells are essential for mammalian sperm production and may have application for treating male infertility.

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Safety and feasibility of performing two consecutive ovarian stimulation cycles with the use of letrozole gonadotropin protocol for fertility preservation in breast cancer patients

Wednesday, November 27, 2013

Capsule:
Performing consecutive cycles of ovarian stimulation with letrozole and gonadotropin protocol for fertility preservation to maximize oocyte yield before chemotherapy is a feasible approach in women with breast cancer.…

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Effective method for emergency fertility preservation random start controlled ovarian stimulation

Wednesday, November 27, 2013
Random-start controlled ovarian stimulation (COS) protocols are as effective as conventional-start COS in fertility preservation and provide a significant advantage by decreasing the total time for embryo/oocyte cryopreservation.

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What do reproductive age women who undergo oocyte cryopreservation think about the process as a means to preserve fertility

Thursday, October 31, 2013
Women electing oocyte cryopreservation know about age-related infertility yet continue to delay childbearing. Fertility preservation can increase a woman’s security regarding her reproductive future.

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Evaluation of cryopreserved ovarian tissue from prepubertal patients after long term xenografting and exogenous stimulation

Thursday, October 31, 2013
After long-term xenotransplantation and exogenous stimulation, a high pool of quiescent follicles and follicular development up to the antral stage were evidenced in cryopreserved ovarian tissue from prepubertal patients.

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Clinical guidelines for sperm cryopreservation in cancer patients

Thursday, October 31, 2013
In clinical guidelines for fertility preservation counseling in male cancer patients, issues of cell damage, contraception, and storage need to be highlighted before and after treatment as part of survivorship.

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Oocyte efficiency does live birth rate differ when analyzing cryopreserved and fresh oocytes on a per oocyte basis

Friday, August 30, 2013
The biological efficiency of oocyte cryopreservation is comparable to fresh in vitro fertilization when live-birth rate is analyzed per mature oocyte retrieved.

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The impact of the culture conditions on early follicle recruitment and growth from human ovarian cortex biopsies in vitro

Wednesday, July 31, 2013
The use of a dynamic fluidic culture system for standardized ovarian cortex biopsies enables both follicle survival and initiation of the earliest follicle development to be better achieved.

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Comparative analysis of fetal and neonatal outcomes of pregnancies from fresh and cryopreserved thawed oocytes in the same group of patients

Wednesday, July 31, 2013
This is an analysis of fetal and neonatal outcomes from fresh and thawed oocyte cycles in the same group of 855 patients.

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Five years experience using oocyte vitrification to preserve fertility for medical and nonmedical indications

Friday, May 31, 2013
Vitrification of oocytes is a reproducible, safe, and efficient method for fertility preservation in both oncological and nononcological patients, with a rapidly increasing demand and proven efficacy.

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Granulocyte colony stimulating factor with or without stem cell factor extends time to premature ovarian insufficiency in female mice treated with alkylating chemotherapy

Friday, May 31, 2013
Treatment of mice with G-CSF with or without SCF protects ovarian follicle pool and extends time to premature ovarian insufficiency in mice treated with alkylating chemotherapy.

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Prospective controlled study to evaluate laboratory and clinical outcomes of oocyte vitrification obtained in in vitro fertilization patients aged 30 to 39 years

Friday, May 31, 2013
In a sibling oocyte study conducted in infertile patients 30–39 years of age, oocyte vitrification had minimal negative impact on embryo development and subsequent clinical results.

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Emergency IVF versus ovarian tissue cryopreservation decision making in fertility preservation for female cancer patients

Tuesday, April 30, 2013
This article examines emergency IVF and ovarian tissue storage and current data on their reproductive outcomes in cancer patients. These data challenge the concept that these techniques should be labeled “experimental.”

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Ovarian stimulation in cancer patients

Tuesday, April 30, 2013
When performing ovarian stimulation for fertility preservation in cancer patients it is critical to understand time constraints, potential complications, risks, and the limited time opportunity.

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Is vitrification of oocytes useful for fertility preservation for age related fertility decline and in cancer patients

Tuesday, April 30, 2013
Vitrification of oocytes is a reproducible, safe, and effective method for fertility preservation in both oncologic and nononcologic patients, with a rapidly increasing demand.

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Fertility preservation from cancer to benign disease to social reasons The challenge of the present decade

Tuesday, April 30, 2013
Predicting the likelihood of infertility following gonadotoxic treatments is extremely difficult. In the present issue, several hot topics in the field of fertility preservation are discussed.

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Current approach to fertility preservation by embryo cryopreservation

Tuesday, April 30, 2013
We review the current state, approach, and indications of embryo cryopreservation for fertility preservation.

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In vitro maturation of oocytes Uncommon indications

Thursday, March 28, 2013
In vitro maturation may be an attractive option in patients suffering from ovarian resistance to FSH and for preserving fertility in combination with ovarian tissue cryopreservation.

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In vitro maturation of human immature oocytes for fertility preservation

Thursday, March 28, 2013
Pregnancies achieved after cryopreservation of in vitro and in vivo matured oocytes are not associated with adverse pregnancy outcomes and may represent a novel strategy of fertility preservation.

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Does early cell death cause germ cell loss after intratesticular tissue grafting

Thursday, March 28, 2013
Spermatogonia-specific apoptosis does not explain the stem cell loss observed after intratesticular tissue grafting. Probably, hypoxia during the first days after transplantation induces degeneration of tubules in the center of the graft.

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Parental attitudes toward fertility preservation in boys with cancer Context of different risk levels of infertility and success rates of fertility restoration

Friday, March 1, 2013
Parents of boys with cancer want some sort of fertility preservation, even if the risks of infertility or the success rates in restoring fertility were 20%.

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Raw and Test Thaw Semen Parameters after Cryopreservation among Men with Newly Diagnosed Cancer

Monday, February 4, 2013
In cryopreserved semen from men with newly diagnosed cancer, all specimens show severe decline in postthaw total motile sperm count, with most severe reductions in the myeloid leukemia group.

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