Social and ethical implications of fertility preservation

Wednesday, June 1, 2016

Authors:
Robert W. Rebar, M.D.…

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Transplantation of frozen thawed ovarian tissue demonstrate high reproductive performance and the need to revise restrictive criteria

Wednesday, April 20, 2016

Authors:
Dror Meirow, M.D.correspondenceemail, Hila Ra’anani, M.D., Moran Shapira, M.D., Masha Brenghausen, Ph.D., Chaim Sanaz Derech, B.Sc., Sarit Aviel-Ronen, M.D., Ph.D., Ninette Amerilgio, M.D., Eyal Schiff, M.D., Raoul Orvieto, M.D., Jehoshua Dor, M.D.…

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Oocytes vitrification as an efficient option for elective fertility preservation

Tuesday, March 1, 2016
A discussion of how oocyte vitrification is clinically efficient for elective fertility preservation in the largest series reported to date and how the demand for this option is increasing.

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Successful elective and medically indicated oocyte vitrification and warming for autologous in vitro fertilization with predicted birth probabilities for fertility preservation according to number of cryopreserved oocytes and age at retrieval

Monday, February 1, 2016
In vitro fertilization using autologous vitrified–warmed oocytes is comparable to treatment using fresh oocytes. Oocyte vitrification is appropriate treatment for indications including unavailability of sperm, limited insemination, and elective fertility preservation.

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Testicular biopsy and cryopreservation for fertility preservation of pre pubertal boys with Klinefelter syndrome A pro con debate

Monday, February 1, 2016
Although fertility preservation techniques in boys and adolescents with Klinefelter syndrome are an emerging field, many technical and ethical issues remain, so these techniques should continue to be viewed as experimental.

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Male adolescent fertility preservation

Monday, February 1, 2016
Today, most male adolescent cancer patients will survive their initial diagnoses. Unfortunately, most of these patients are not currently provided adequate fertility preservation counseling or care.

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Male fertility preservation Innovations and questions

Monday, February 1, 2016
A protocol for cryopreservation of human endometrial epithelial cells allows for successful recovery and establishment of functional characteristics.

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Female fertility preservation Innovations and questions

Tuesday, December 29, 2015
Preserving the potential of becoming genetic mother should now be part of the management of infants, adolescents, and young women at risk for infertility from benign or malignant diseases.

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Prevention of chemotherapy induced ovarian damage

Tuesday, December 29, 2015
We discuss methods for the prevention of chemotherapy-induced ovarian damage, including agents that act on the PI3K/PTEN/Akt follicle activation pathway, apoptotic pathways, the vascular system, and other potential methods of reducing chemotherapy-induced ovotoxicity.

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Fertility preservation in Turner syndrome

Tuesday, December 29, 2015
Fertility preservation in patients with Turner syndrome represents an important issue even if it is particularly complex due to the rapid and profound exhaustion of the pool of follicles.

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Fertility preservation in pre pubertal girls with cancer The role of ovarian tissue cryopreservation

Tuesday, December 29, 2015
We discuss the indications for ovarian tissue cryopreservation in young patients with cancer, and future potential uses for this tissue.

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Access to fertility services by transgender persons An Ethics Committee opinion

Thursday, October 29, 2015
This statement explores the provision of fertility services to transgender persons.

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Cryopreservation of testicular tissue before long term testicular cell culture does not alter in vitro cell dynamics

Thursday, October 29, 2015
Cryopreservation of testicular tissue before culture does not influence the cell composition in longterm testicular cell cultures.

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Live birth following in vitro maturation of oocytes retrieved from extracorporeal ovarian tissue aspiration and embryo cryopreservation for 5 years

Thursday, October 29, 2015
Extracorporeal aspiration of immature oocytes from ovarian tissue, in vitro maturation, embryo cryopreservation, and a delayed frozen embryo transfer ultimately led to a live birth.

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Freezing and thawing testicular cells may not affect growth of cultured testicular cells

Thursday, October 29, 2015

Authors:
James F. Smith, M.D., M.S., Nam D.…

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Ovarian cortex transplantation Time to move on from experimental studies to open clinical application

Thursday, October 29, 2015

Authors:
Jacques Donnez, M.D., Ph.D., Marie-Madeleine Dolmans, M.D., Ph.D., César Diaz, M.D., Ph.D., Antonio Pellicer, M.D., Ph.D.…

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Safety of ovarian conservation and fertility preservation in advanced borderline ovarian tumors

Monday, June 29, 2015
Fertility-sparing surgery was not associated with compromised outcome in this series of 59 patients with advanced borderline ovarian tumor, and it allowed the attainment of 26 live births.

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Baby budgeting Oocyte cryopreservation in women delaying reproduction can reduce cost per live birth

Monday, June 1, 2015
This cost analysis demonstrates that in women who plan to delay childbearing until age 40 years, oocyte cryopreservation before 38 years of age can reduce the cost to obtain a live birth.

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Optimal timing for elective egg freezing

Monday, June 1, 2015
Based on a decision-tree analysis, elective egg freezing is most successful if performed before the age of 34 years but is most cost-effective at the age of 37 years.

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Xenotransplantation of cryopreserved human ovarian tissue A systematic review of MII oocyte maturation and discussion of it as a realistic option for restoring fertility after cancer treatment

Monday, June 1, 2015
This review discusses the value of xenotransplantation as a tool in reproductive biology and ethical and potential safety issues associated with ovarian tissue xenotransplantation as a means of restoring fertility.

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Long term cryopreservation of human oocytes does not increase embryonic aneuploidy

Friday, February 27, 2015
Embryos derived from cryopreserved oocytes demonstrate impaired blastulation but equivalent rates of euploidy, implantation, and live birth compared with fresh oocytes, supporting the safety and efficacy of oocyte cryopreservation.

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Optimizing human semen cryopreservation by reducing test vial volume and repetitive test vial sampling

Friday, February 27, 2015
Optimal cryopreservation test vial volume is 100 mL; results from one test vial appear to be sufficiently predictive of post-thaw quality for multiple ejaculates frozen over 10 days.

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Pregnancies and live births after 20 transplantations of cryopreserved ovarian tissue in a single center

Friday, January 30, 2015
Preserving fertility by cryopreserving ovarian tissue is a successful and safe clinical option that can be considered for selected cancer patients.

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Sperm cryopreservation in adolescents and young adults with cancer Results of the French national sperm banking network CECOS

Friday, January 30, 2015
Sperm banking is possible in young adolescents. The discrepancy between cancer incidence and the proportion of adolescents referred for sperm banking highlights the need for a change in care policy.

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Granulocyte colony stimulating factor prevents loss of spermatogenesis after sterilizing busulfan chemotherapy

Monday, December 29, 2014
Spermatogenesis can be destroyed by alkylating chemotherapies. In this study, spermatogenesis and undifferentiated spermatogonia in mice treated with busulfan were protected by treatment with granulocyte colony-stimulating factor.

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Tamoxifen coadministration during controlled ovarian hyperstimulation for in vitro fertilization in breast cancer patients increases the safety of fertility preservation treatment strategies

Wednesday, July 30, 2014
In nonmenopausal breast cancer patients, tamoxifen effectively reduces cancer risk despite chronically extremely high E2 levels. Tamoxifen co-administration during conventional COH for IVF is effective without increasing risks to patients.

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Comparison of starting ovarian stimulation on day 2 versus day 15 of the menstrual cycle in the same oocyte donor and pregnancy rates among the corresponding recipients of vitrified oocytes

Wednesday, July 9, 2014
Starting ovarian stimulation on days 2 or 15 of the menstrual cycle yielded similar oocyte numbers in same oocyte donors with encouraging pregnancy rates in recipients of the vitrified oocytes.

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Prospective study of depression and anxiety in female fertility preservation and infertility patients

Tuesday, July 8, 2014
Fertility preservation patients report higher levels of depression and anxiety at the onset of treatment than infertility patients, but infertility patients’ symptoms worsen across treatment.

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Semen quality of consecutive ejaculates from cancer patients for fertility preservation

Monday, June 30, 2014
This is the first study showing that repeated ejaculates from cancer patients did not show substantial variation in semen quality.

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Defining the specific reproductive effects of cancer therapies The burden is upon us

Tuesday, June 24, 2014
Reflections on "Impact of lymphoma treatments on spermatogenesis and sperm DNA: a multicenter prospective study from the CECOS network" by Bujan et al.

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