Epithelial cell protein milk fat globule epidermal growth factor 8 and human chorionic gonadotropin regulate stromal cell apoptosis in the human endometrium

Thursday, November 29, 2012
Milk fat globule–epidermal growth factor 8, a multifunctional epithelial protein in the human endometrium, and hCG modulate apoptosis of stromal cells.

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Endometrial reconstruction from stem cells

Thursday, June 28, 2012
Adult stem cells have been identified in human endometrium. Their ability to reconstruct endometrial tissue when transplanted into immunocompromised animals suggests their potential use for treating disorders associated with inadequate endometrium.

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Proteomic identification of neurotrophins in the eutopic endometrium of women with endometriosis

Friday, June 8, 2012
Proteomic analysis of neurotrophins within the functional layer of the endometrium identified two factors that are expressed differentially in the eutopic endometrium of women with endometriosis compared to controls.

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Expression of Phosphoinositide-specific Phospholipase C enzymes in normal endometrium and in endometriosis

Friday, June 8, 2012
The different expression of PI-PLC enzymes in the endometrium and endometriosis tissue suggests the hypothesis that PI-PLC enzymes, main effectors in PI signaling, might be involved in the pathogenesis of endometriosis.

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Expression and activation of the membrane-cytoskeleton protein ezrin during the normal endometrial cycle

Monday, June 4, 2012
Ezrin/phospho-ezrin immunoreactivity are present on apical surfaces of the luminal epithelium, around secretory vacuoles and in luminal secretions during the secretory phase. These findings have functional implications for implantation biology.

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Androgen signaling in decidualizing human endometrial stromal cells enhances resistance to oxidative stress

Friday, June 1, 2012
Androgens inhibit cell death of decidualizing endometrial stromal cells exposed to oxidative stress signals. Therefore, androgens might play a critical role for decidua processes of embryo implantation and trophoblast invasion.

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Physiologic activation of nuclear factor kappa-B in the endometrium during the menstrual cycle is altered in endometriosis patients

Wednesday, May 23, 2012
Healthy endometrium has variable constitutive nuclear factor kB activity. Altered p65 activity in secretory endometrium from endometriosis patients may modulate endometrial dysfunctions associated with endometriosis pathophysiology.

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Defective endometrial receptivity

Friday, May 4, 2012
Defective endometrial receptivity is secondary to intrauterine pathology or aberrant development of adhesive properties at the molecular level. Investigation and treatment of endometrial pathology will increase IVF success rates.

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