Estrogen receptor β regulates endometriotic cell survival through serum and glucocorticoid regulated kinase activation

Sunday, May 1, 2016
Estrogen receptor (ER) b is aberrantly overexpressed in ectopic endometriotic tissues. This study demonstrates that ERb regulates the transcription of SGK1, a kinase that promotes apoptotic resistance in endometriosis via FOXO3 inactivation.

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Administration of atosiban in patients with endometriosis undergoing frozen thawed embryo transfer A prospective randomized study

Wednesday, April 13, 2016

Authors:
Ye He, M.D., Huan Wu, M.D., Xiaojin He, M.D., Ph.D, Qiong Xing, M.D., Ping Zhou, M.D., Yunxia Cao, M.D., Ph.D., Zhaolian Wei, M.D., Ph.D.…

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Serum microRNAs as diagnostic markers of endometriosis A comprehensive array based analysis

Tuesday, April 12, 2016

Authors:
Emine Cosar, M.D., Ramanaiah Mamillapalli, Ph.D., Gulcin Sahin Ersoy, M.D., SihYun Cho, M.D., Benjamin Seifer, B.S., Hugh S.…

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The risks of tubo ovarian abscess in case of endometrioma and assisted reproductive technologies are both under and overreported

Tuesday, April 12, 2016

Authors:
Claire Villette, M.D., Antoine Bourret, M.D., Pietro Santulli, M.D., Ph.D., Vanessa Gayet, M.D., Charles Chapron, M.D., Dominique de Ziegler, M.D.…

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Age independent from ovarian reserve status is the main prognostic factor in natural cycle in vitro fertilization

Tuesday, April 5, 2016

Authors:
Iñaki González-Foruria, M.D., Juana Peñarrubia, M.D., Aina Borràs, M.D., Dolors Manau, M.D., Gemma Casals, M.D., Sara Peralta, M.D., Montserrat Creus, M.D., Janisse Ferreri, M.D., Ester Vidal, Ph.D., Francisco Carmona, M.D., Juan Balasch, M.D., Francisco Fàbregues, M.D.…

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Endometrial expression and in vitro modulation of the iron transporter divalent metal transporter 1 Implications for endometriosis

Friday, April 1, 2016

Authors:
Carlos Patricio Alvarado-Díaz, Ph.D., Marco Tulio Núñez, Ph.D., Luigi Devoto, M.D., Reinaldo González-Ramos, M.D., Ph.D.…

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Endometriosis related infertility Assisted reproductive technology has no adverse impact on pain and quality of life scores

Friday, April 1, 2016
Assisted reproduction technology has no adverse impact on pain symptoms or quality of life in women with endometriosis of any phenotype as compared with healthy women.

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Surgical removal of endometriotic lesions alters local and systemic proinflammatory cytokines in endometriosis patients

Friday, April 1, 2016
Excising endometriotic lesions significantly decreased circulating levels of inflammatory cytokines. Levels were also higher than in normal women, dissimilar in eutopic versus ectopic endometrium, and influenced by disease stage.

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Potential influence of in utero and early neonatal exposures on the later development of endometriosis

Friday, April 1, 2016
Women with endometriosis, in addition to genetic predisposition, are exposed more frequently to preterm birth during intrauterine life and to formula feeding in early postnatal life.

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Vascular endothelial growth factor pathway in endometriosis Genetic variants and plasma biomarkers

Friday, April 1, 2016
Our study showed that, in Caucasian women, genetic variants in the PLGF rs2268613 gene influences PLGF plasma levels. Plasma levels of VEGF were elevated in endometriosis patients compared with controls.

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Optimal uterine anatomy and physiology necessary for normal implantation and placentation

Friday, April 1, 2016
Anatomic and functional anomalies of the uterus, including those occurring as a result of pathologies lying outside the uterus, such as endometriosis and hydrosalpinges, should be elucidated, with appropriate measures taken to optimize assisted reproductive outcome.

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Risk of miscarriage in women with endometriosis Insights from in vitro fertilization cycles

Tuesday, March 29, 2016

Authors:
Marta Leonardi, M.D., Enrico Papaleo, M.D., Marco Reschini, M.Sc., Luca Pagliardini, M.D., Laura Benaglia, M.D., Giorgio Candotti, M.D., Paola Viganó, D.Sc., Ph.D., Lavinia Quaranta, M.D., Maria Munaretto, M.D., Massimo Candiani, M.D., Paolo Vercellini, M.D., Edgardo Somigliana, M.D.…

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Impact of endometriosis on in vitro fertilization outcomes An evaluation of the Society for Assisted Reproductive Technologies Database

Monday, March 21, 2016

Authors:
Suneeta Senapati, M.D., M.S.C.E., Mary D.…

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Syndecan 4 expression is upregulated in endometriosis and contributes to an invasive phenotype

Wednesday, March 16, 2016

Authors:
Anca Chelariu-Raicu, M.D., Cornelia Wilke, Ph.D., Melanie Brand, M.Sc., Anna Starzinski-Powitz, Ph.D., Ludwig Kiesel, M.D., Ph.D., Andreas N.…

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C Jun NH2 terminal Kinase JNK inhibitor Bentamapimod reduces induced endometriosis in baboons An assessor blind placebo controlled randomized study

Tuesday, March 1, 2016
We discuss how c-Jun NH2-terminal kinase inhibition reduces endometriosis without hormonal suppression.

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Norethindrone acetate or dienogest for the treatment of symptomatic endometriosis A before and after study

Tuesday, March 1, 2016
Systematic change from norethindrone acetate to dienogest as first-choice progestin for endometriosis was associated with enhanced drug tolerability and similar improvement in pain relief, quality of life, and patient satisfaction.

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Microscopic endometriosis Impact on our understanding of the disease and its surgery

Monday, February 1, 2016

Authors:
Philippe R. Koninckx, M.D., Ph.D., Jacques Donnez, M.D., Ph.D., Ivo Brosens, M.D., Ph.D.…

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Expression of microtubule associated protein 2 and synaptophysin in endometrium High levels in deep infiltrating endometriosis lesions

Monday, February 1, 2016
Nerve growth factor, microtubule associated protein 2, and synaptophysin messenger RNAs and proteins are expressed in healthy endometrium and in endometriosis, being highest in deep lesions.

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Bowel occult microscopic endometriosis in resection margins in deep colorectal endometriosis specimens has no impact on short term postoperative outcomes

Monday, February 1, 2016
In women with colorectal endometriosis, bowel resection margins of colorectal resection specimens presented occult microscopic endometriosis implants in 14.6% of cases with no impact on short-term clinical outcomes.

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Assessing brain derived neurotrophic factor as a novel clinical marker of endometriosis

Tuesday, December 29, 2015
We discuss how brain-derived neurotrophic factor is a better predictor of endometriosis than nerve growth factor, neurotrophin 4/5, cancer antigen 125, and C-reactive protein in a cohort of 138 women.

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Endometriosis may not be a chronic disease An alternative theory offering more optimistic prospects for our patients

Tuesday, December 29, 2015

Authors:
Michel Canis, M.D., Ph.D., Nicolas Bourdel, M.D., Céline Houlle, M.D., Anne Sophie Gremeau, M.D., Revaz Botchorishvili, M.D., Sachiko Matsuzaki, M.D.…

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Evidence of a genetic link between endometriosis and ovarian cancer

Tuesday, December 29, 2015
There is a clear genetic link between endometriosis and risk of ovarian cancer, especially for the highgrade serous and clear cell histotypes.

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Second live birth after undergoing assisted reproductive technology in women operated on for endometriosis

Tuesday, December 29, 2015
Endometriosis fertility index could be used in infertility work-up for a second live birth, after the first child was obtained through assisted reproductive technology.

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Nuclear magnetic resonance metabolomic profiling of urine provides a noninvasive alternative to the identification of biomarkers associated with endometriosis

Thursday, October 29, 2015
A comparative analysis of urine metabolomic profiles, based on 1H-NMR spectroscopy, of endometriosis patients and healthy women facilitates the noninvasive identification of metabolites discriminating both groups.

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Evaluation of the potential therapeutic effects of a double stranded RNA mimic complexed with polycations in an experimental mouse model of endometriosis

Thursday, October 29, 2015
Polyethyleneimine prevented angiogenesis and promoted apoptosis in a mouse model of endometriosis, but prolonged treatments over time may be necessary to detect an effect of this compound on lesion size.

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Laparoscopic anatomy of the autonomic nerves of the pelvis and the concept of nerve sparing surgery by direct visualization of autonomic nerve bundles

Thursday, October 29, 2015

Original Video Article

Capsule:
Educational video demonstrating the anatomy of the autonomic nerves of he pelvis and the laparoscopic neuronavigation technique for nerve-sparing radical endometriosis surgery.…

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Prevention of the recurrence of symptom and lesions after conservative surgery for endometriosis

Tuesday, September 29, 2015
Endometriosis frequently recurs after conservative surgery. Long-term medical therapy until the patient wishes to conceive is recommended to prevent the recurrence of symptoms and lesions of endometriosis.

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Beyond infertility Obstetrical and postpartum complications associated with endometriosis and adenomyosis

Tuesday, September 29, 2015
During pregnancy, women with endometriosis may undergo severe complications, such as spontaneous hemoperitoneum, and seem to be at higher risk of preterm birth and placenta previa.

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Management of endometriosis Towards a problem oriented and patient centered approach

Tuesday, September 29, 2015
Endometriosis management should not be focused exclusively on lesions; a problem-oriented approach should be adopted; and quantitative information on alternative treatments must be provided to allow for a shared decision-making process.

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Heritability of endometriosis

Tuesday, September 29, 2015
Genetic and unique environmental influences on the etiology of endometriosis further strengthen the conclusion that genes have a strong influence on the phenotypic manifestations of endometriosis.

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