Both slowly developing embryos and a variable pace of luteal endometrial progression may conspire to prevent normal birth in spite of a capable embryo

Friday, April 1, 2016
Embryonic implantation requires synchrony between the endometrium and the embryo.

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Hepatitis B surface antigen in oocytes and embryos may not result in vertical transmission to offspring of hepatitis B virus carriers

Friday, April 1, 2016
Children from oocytes and embryos infected with hepatitis B virus (HBV) were not chronically infected after birth; the HBsAg in oocytes and embryos may not result in vertical transmission.

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Time lapse deselection model for human day 3 in vitro fertilization embryos The combination of qualitative and quantitative measures of embryo growth

Tuesday, March 1, 2016
This study presents a deselection model for human in vitro fertilization embryos independent of the insemination method, the qualitative component being more accurate when coupled with a quantitative component.

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Time lapse the remaining questions to be answered

Monday, February 1, 2016

Author:
Marcos Meseguer, Ph.D

Volume 105, Issue 2, Pages 295-296

Abstract:

Reflections on “Does the addition of time-lapse morphokinetics in the selection of embryos for transfer improve pregnancy rates?…

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Aberrant sperm DNA methylation predicts male fertility status and embryo quality

Monday, November 30, 2015
Genome wide sperm DNA patterns in fertile and infertile men are highly predictive of fertility status and may predict embryonic developmental capacity during IVF.

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Clinical significance of intercellular contact at the four cell stage of human embryos and the use of abnormal cleavage patterns to identify embryos with low implantation potential A time lapse study

Monday, June 1, 2015
Reduced intercellular contact in four-cell stage human embryos leads to compromised subsequent development and implantation potential. Implantation rates could be improved by not selecting embryos showing abnormal cleavage patterns.

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Frozen thawed day 5 blastocyst transfer is associated with a lower risk of ectopic pregnancy than day 3 transfer and fresh transfer

Friday, February 27, 2015
Frozen-thawed day 5 blastocyst transfer is associated with a lower ectopic pregnancy rate than frozen- thawed day 3 transfer and fresh transfer in patients undergoing IVF-ET.

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Omics as a window to view embryo viability

Friday, January 30, 2015
Omics technologies offer several noninvasive platforms for the investigation of biomarkers for embryo viability.

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Oocyte competency is the key to embryo potential

Friday, January 30, 2015
The oocyte is the major determinant of embryo developmental competence. Technology has improved the noninvasive assessment of oocyte quality. Analysis of polar body DNA may provide insight into the prediction of embryo developmental competence.

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Fragmentation of human cleavage stage embryos is related to the progression through meiotic and mitotic cell cycles

Friday, January 30, 2015
The appearance of the meiotic spindle and the durations of the first, second, and third mitoses are related to the degree of fragmentation of human embryos.

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Chromothripsis Potential origin in gametogenesis and preimplantation cell divisions A review

Tuesday, November 25, 2014
The role of chromothripsis, a heretofore unexpected cause of massive chromosomal rearrangements, and its potential impact on gametogenesis and early embryonic development are explored in this review.

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Role of assisted hatching in in vitro fertilization A guideline

Wednesday, July 30, 2014
This guideline document reviews the safety and efficacy of assisted hatching.

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Next generation sequencing The dawn of a new era for preimplantation genetic diagnostics

Wednesday, April 30, 2014
Reflections on "Development and validation of a next-generation sequencing–based protocol for 24-chromosome aneuploidy screening of embryos" by Fiorentino et al.

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Effects of assisted reproductive technologies on human sex ratio at birth

Wednesday, April 30, 2014
The authors analyzed the gender of more than 100,000 babies in the United Kingdom born after ART and found that the type of ART treatment used can affect the sex ratio.

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Misconduct in third party assisted reproduction a committee opinion

Tuesday, December 31, 2013
This document discusses the responsibilities of the physician in situations of third-party assisted reproduction where malfeasance or misconduct has occurred.

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Preliminary investigation of the impact of anticentromere antibody on oocyte maturation and embryo cleavage

Wednesday, November 27, 2013
Decreased percentage of mature oocytes and rate of embryo cleavage were found in the ACA[+]/ANA[+] group as compared with the ACA[]/ANA[+] group.

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Access to fertility treatment by gays lesbians and unmarried persons a committee opinion

Wednesday, November 27, 2013
This statement explores the implications of reproduction by single individuals, unmarried heterosexual couples, and gay and lesbian couples.

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Developmental exposure of fetal ovaries and fetal germ cells to endometriosis in an endometriosis model causes differential gene expression in the preimplantation embryos of the first generation and second generation embryos

Thursday, October 31, 2013
Fetal and fetal germ cell exposure to endometriosis in utero alters gene expression in first- and second-generation eight-cell embryos.

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Aging sperm negatively impacts in vivo and in vitro reproduction a longitudinal murine study

Friday, June 28, 2013
Natural male aging negatively affects both in vivo and in vitro reproductive outcomes in an outbred murine model.

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Consideration of the gestational carrier a committee opinion

Friday, May 31, 2013
This statement considers the protective safeguards that need to be in place to ensure the ethical treatment of gestational carriers.

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Embryology in the era of proteomics

Monday, March 18, 2013
A review of the contribution of proteomic technologies in the identification of the human embryonic secretome.

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Blastocyst culture and transfer in clinical assisted reproduction

Friday, March 1, 2013
Blastocyst embryo transfer improves the live-birth rate in good prognosis patients compared with cleavage-stage transfer. In unselected or poor prognosis patients, it is not proven superior to cleavage-stage transfer.

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Effect of 5-aza-2′-deoxycytidine on methylation of the putative imprinted control region of H19 during the in vitro development of vitrified bovine two-cell embryos

Thursday, June 7, 2012
H19 imprinted control region methylation levels significantly increased in vitrified two-cell embryos and their derived blastocysts; 5-aza-dC significantly reduced H19 imprinted control region methylation and increased H19 expression in blastocysts derived from vitrified embryos.

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Comparison of Cryotip vs. Cryotop for mouse and human blastomere vitrification

Monday, June 4, 2012
We have compared open vs. closed systems for mouse and human blastomere vitrification and conclude that the closed system is more efficient in terms of blastomere survival and division.

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Full in vitro fertilization laboratory mechanization: toward robotic assisted reproduction?

Wednesday, May 30, 2012
Technologies related to automation, such as nonsubjective sperm selection, oocyte fertilization, and embryo culture and monitoring, are available, and this means that sample preparation, chemical or biologic reactions, and data collection could be integrated.

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Recurrent implantation failure: gamete and embryo factors

Thursday, May 10, 2012
Recurrent implantation failure in IVF may be partially attributed to oocyte, sperm, and embryonic factors. Possible etiologies are reviewed and discussed, and recent advances in oocyte and embryo selection are evaluated along with current recommended management strategies.

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