Effectiveness of in vitro fertilization with preimplantation genetic screening A reanalysis of United States assisted reproductive technology data 2011 2012

Monday, February 15, 2016

Authors:
Vitaly A. Kushnir, M.D., Sarah K.…

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Improved implantation rates of day 3 embryo transfers with the use of an automated time lapse enabled test to aid in embryo selection

Monday, February 1, 2016
An automated noninvasive time-lapse embryo assessment test can be used together with embryo morphology to increase implantation rates after day 3 transfer.

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Does the addition of time lapse morphokinetics in the selection of embryos for transfer improve pregnancy rates A randomized controlled trial

Monday, February 1, 2016
This randomized controlled trial could not detect a statistically significant difference in reproductive outcomes when continuous time-lapse morphokinetic data was added to conventional screening criteria for embryo selection.

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Comprehensive chromosome screening improves embryo selection A meta analysis

Monday, November 30, 2015
In patients with normal ovarian reserve, comprehensive chromosome screening increases clinical and sustained implantation rates, thus improving embryo selection.

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Choosing the best embryo by time lapse versus standard morphology

Friday, January 30, 2015
Retrospective studies have shown correlation between time-lapse parameters and embryo viability. A recent randomized study has shown improved pregnancy rates. Strict evidence still seems weak.

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Clinical validation of embryo culture and selection by morphokinetic analysis A randomized controlled trial of the EmbryoScope

Wednesday, July 9, 2014
An alternative strategy for embryo selection based on a multivariable morphokinetic model combined with continuous incubation in an integrated timelapse monitoring system improves the clinical results.

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Atypical embryo phenotypes identified by time lapse microscopy High prevalence and association with embryo development

Sunday, June 1, 2014
Time-lapse microscopy is used to identify and define atypical human embryo phenotypes that may aid in the deselection of poorer quality embryos, thereby improving in vitro embryo selection.

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Assessment of the implantation of day 2 human embryos by morphometric nonsubjective parameters

Monday, May 12, 2014
The aim of this work is to define what objective variables, obtained by image analysis, show better predictive value of embryo quality for implantation in women age <36 years. Smaller circular embryos with thinner zona pellucida are more likely to implant.

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The effect of the biochemical marker soluble human leukocyte antigen G on pregnancy outcome in assisted reproductive technology a multicenter study

Thursday, October 31, 2013
Data from 2,040 intracytoplasmic sperm injection patients combining embryo morphology with expression of sHLA-G (a noninvasive embryo marker) show improved pregnancy outcome and the theoretical potential to reduce multiple pregnancies.

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Improving embryo selection using a computer automated time lapse image analysis test plus day 3 morphology Results from a prospective multicenter trial

Wednesday, July 31, 2013
Noninvasive computer-automated measurement of cell cycle times, in combination with standard morphological evaluation, significantly improves day 3 embryo selection compared with standard morphological evaluation alone.

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The assisted reproduction technology laboratory toward evidence based practice

Wednesday, July 31, 2013
In the human assisted reproduction laboratory, should equipment, utensils, and consumables, as well as culture and embryo selection strategies, be systematically evaluated before being introduced into routine use?

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One swallow does not make a summer

Thursday, March 28, 2013
Reflections on "Preimplantation genetic screening using fluorescence in situ hybridization in patients with repetitive implantation failure and advanced maternal age: two randomized trials" by Rubio et al.

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Four hour quantitative real time polymerase chain reaction based comprehensive chromosome screening and accumulating evidence of accuracy safety predictive value and clinical efficacy

Monday, March 18, 2013
This review summarizes the accumulated experience with the development and clinical application of a 4-hour blastocyst quantitative real-time polymerase chain reaction–based comprehensive chromosome screening technology.

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Biomarkers identified with time lapse imaging Discovery validation and practical application

Monday, March 18, 2013
Time-lapse markers that are supported by basic research, validated through prospective clinical studies, and accompanied by a reliable quantification technology may improve embryo selection and IVF success.

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Analysis of metabolism to select viable human embryos for transfer

Monday, March 18, 2013
Metabolic activity of an embryo is reflective of its sex and developmental potential. We review how the culture environment can affect patterns of nutrient utilization and metabolism, and thus viability.

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Embryo incubation and selection in a time lapse monitoring system improves pregnancy outcome in comparison with a standard incubator A retrospective cohort study

Thursday, November 29, 2012
Logistic regression analyses of retrospective data from ten IVF clinics indicate significant improvement in clinical pregnancy rate (relative +20%), presumably from stable culture conditions and morphokinetic selection, with the use of time-lapse embryo monitoring.

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