Sequential versus Monophasic Media Impact Trial SuMMIT A paired randomized controlled trial comparing a sequential media system to a monophasic medium

Sunday, May 1, 2016
This study demonstrates that the usable blastocyst rate is greatest after culture in sequential media in comparison with monophasic; however, no difference exists in timing of blastulation, aneuploidy, or sustained implantation rate.

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Low versus atmospheric oxygen tension for embryo culture in assisted reproduction A systematic review and meta analysis

Wednesday, February 24, 2016

Authors:
Carolina O. Nastri, Ph.D., Beatrice N.…

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Clinical validation of embryo culture and selection by morphokinetic analysis A randomized controlled trial of the EmbryoScope

Wednesday, July 9, 2014
An alternative strategy for embryo selection based on a multivariable morphokinetic model combined with continuous incubation in an integrated timelapse monitoring system improves the clinical results.

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Composition of commercial media used for human embryo culture

Tuesday, May 27, 2014
There is considerable biologically relevant variation in the compositions of commercially available culture media. This information provides a framework for future analysis of long-term effects of in vitro culture and optimization of culture media.

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Variability in protein quality used for embryo culture Embryotoxicity of the stabilizer octanoic acid

Wednesday, July 31, 2013
Octanoic acid, a stabilizer in albumin preparations, inhibits embryo development; because concentrations of octanoic acid vary among lots, it is a defined embryo toxin for routine screening.

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Mouse strain and quality control testing improved sensitivity of the mouse embryo assay with embryos from outbred mice

Friday, March 1, 2013
Embryos from outbred mice are sensitive to in vitro toxins and may provide a more reliable measure of quality for undefined culture components such as mineral oil.

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Effect of oxygen concentration on human embryo development evaluated by time lapse monitoring

Friday, March 1, 2013
With the use of time-lapse monitoring, to evaluate human embryo development, we describe a stage-dependent adverse response to atmospheric oxygen.

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