Regulatory role of microRNAs in ovarian function

Sunday, June 1, 2014
MicroRNAs have a fundamental role in the regulation of gene expression in the ovary. Research on the role in physiological and dysfunctional ovulation may offer new diagnostic and therapeutic strategies.

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Endocrine disruptors and human reproductive failure The in vitro effect of phthalates on human luteal cells

Tuesday, May 27, 2014
GnRH receptor analysis showed deleterious mutations in 10% of normosmic isolated hypogonadotropic hypogonadism patients, with a good genotype-phenotype correlation. No significant alterations were identified in constitutional delay of growth and puberty.

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Delta like ligand 4 regulates vascular endothelial growth factor receptor 2 driven luteal angiogenesis through induction of a tip stalk phenotype in proliferating endothelial cells

Wednesday, November 27, 2013
Blockade of Dll4 in an in vivo rodent model shows that VEGFR2-mediated sprouting during luteal angiogenesis is modulated by the Dll4/Notch-1 pathway, which induces a tip/stalk phenotype.

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Kisspeptin stimulates progesterone secretion via the Erk1 2 mitogen activated protein kinase signaling pathway in rat luteal cells

Thursday, March 28, 2013
Kisspeptin could augment progesterone secretion via stimulating key steroidogenic enzymes and phosphorylate Erk1/2 mitogen-activated protein kinase in cultured luteal cells.

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In vitro effect of unacylated ghrelin and obestatin on human luteal cell function

Friday, May 11, 2012
Unacylated ghrelin and obestatin influence human luteal cell function in vitro.

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