Blastocoel fluid from differentiated blastocysts harbors embryonic genomic material capable of a whole genome deoxyribonucleic acid amplification and comprehensive chromosome microarray analysis

Thursday, July 30, 2015
A molecular karyotype can be obtained from genomic deoxyribonucleic acid isolated from the blastocoel fluid, which may provide insight into embryonic development and demonstrate the potential for future less invasive preimplantation genetic testing.

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Increased blastomere number in cleavage-stage embryos is associated with higher aneuploidy

Friday, February 27, 2015
In this study of blastomere number and aneuploidy, rapidly developing cleavage-stage embryos are more likely to progress to blastocysts and are more likely to be chromosomally abnormal.

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Miscarriage chromosome testing Utility of comparative genomic hybridization with reflex microsatellite analysis in preserved miscarriage tissue

Wednesday, April 30, 2014
This observational study shows that comparative genomic hybridization and reflex microsatellite analysis are effective DNA technologies to determine chromosome results of preserved miscarriage tissue.

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The Effect of Timing of Embryonic Progression on Chromosomal Abnormality

Thursday, September 27, 2012
In this study analyzing embryo morphology and chromosomal status in relation to rate of embryonic developmental progression, the ability to blastulate, rather than day of blastulation, was found to significantly affect aneuploidy.

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