Protocols to induce ovulation and progesterone block experiments

Tuesday, April 12, 2016

Author:
Daniela Galliano, MD, PhD

Abstract:

Clomiphene citrate (CC) was an emerging area of research in the 1960s.…

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Effects of fertility drugs on cancers other than breast and gynecologic malignancies

Tuesday, September 29, 2015
Ovulation-stimulating drugs were unrelated to lung or colorectal cancer risks, but possibly related to slight risk increases for melanomas and thyroid cancers, supporting the need for further evaluation of these cancers.

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Mild ovarian stimulation with clomiphene citrate launch is a realistic option for in vitro fertilization

Thursday, July 30, 2015
Mild stimulation using clomiphene citrate can be considered a realistic option to give patients with a good prognosis an excellent probability of pregnancy in a very short time period.

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Assessment of multiple intrauterine gestations from ovarian stimulation AMIGOS trial Baseline characteristics

Monday, March 30, 2015
The baseline characteristics are provided for women with unexplained infertility who participated in the AMIGOS trial examining ovarian stimulation with gonadotropins, CC, and letrozole.

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Testing and interpreting measures of ovarian reserve A committee opinion

Friday, February 27, 2015

Authors:
Practice Committee of the American Society for Reproductive Medicine

Volume 103, Issue 3, Page e9

Abstract:

Currently there is no uniformly accepted definition of decreased ovarian reserve (DOR), as the term may refer to three related but distinctly different outcomes: oocyte quality, oocyte quantity, or reproductive potential.…

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Ovulation rate and cycle characteristics in a subsequent clomiphene citrate cycle after stair step protocol

Friday, February 27, 2015
The ovulatory dose in the clomiphene citrate (CC) stair-step protocol is effective in inducing ovulation in most patients undergoing a subsequent CC cycle.

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Perinatal outcomes in 6338 singletons born after intrauterine insemination in Denmark 2007 to 2012 The influence of ovarian stimulation

Friday, June 20, 2014
Treatment with clomiphene citrate is associated with an increased risk of small for gestational age in children born after intrauterine insemination, whereas ovarian stimulation with follicle-stimulating hormone did not seem to increase the risk of adverse perinatal outcomes.

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Ovulation inducing drugs and ovarian cancer risk results from an extended followup of a large United States infertility cohort

Wednesday, November 27, 2013
Our findings were generally reassuring in not confirming a link between ovulation-inducing drugs and ovarian cancer; risk was increased, however, among women who, despite having used clomiphene citrate, remained nulligravid.

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The basic fertility workup in women with polycystic ovary syndrome a systematic review

Friday, June 28, 2013
In subfertile women with anovulation we evaluated the prevalence of additional fertility-reducing factors and the diagnostic and prognostic capacity of fertility tests.

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Clomiphene citrate potentiates the adverse effects of estrogen on rat testis and down regulates the expression of steroidogenic enzyme genes

Wednesday, January 2, 2013
The effects of clomiphene citrate on testicular function and steroidogenic enzyme gene expression were investigated in rats estrogenized with estradiol-3-benzoate.

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A historical perspective of aromatase inhibitors for ovulation induction

Thursday, November 29, 2012
This review provides a brief history of the development of letrozole for ovulation induction.

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Temporal trends in clomiphene citrate use: a population-based study

Wednesday, May 23, 2012
Increased incidence rates of clomiphene citrate use among women aged 30 to 44 years over the past decade indicate a growing demand for fertility treatments in this population.

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What is the optimal follicular size before triggering ovulation in intrauterine insemination cycles with clomiphene citrate or letrozole? An analysis of 988 cycles

Friday, May 4, 2012
The optimal size of the leading follicle in cycles with clomiphene citrate and letrozole is in the range of 23–28 mm and is closely related to the endometrial thickness.

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