Factors associated with birth outcomes from cryopreserved blastocysts Experience from 4597 autologous transfers of 7597 cryopreserved blastocysts
Wednesday, April 13, 2016
Kevin S. Richter, Ph.D., Daniella K.…
Distribution patterns of segmental aneuploidies in human blastocysts identified by next generation sequencing
Friday, April 1, 2016Next-generation sequencing allows for the detection of pure and mosaic segmental aneuploidies with the same efficiency as array comparative genomic hybridization.
Examining the many potential reasons why euploid blastocysts do not always result in viable pregnancies Part 1
Tuesday, March 1, 2016The environment surrounding the oocyte and embryo from months before ovarian stimulation to embryo transfer profoundly affects the proportion of euploid embryos that fail to result in viable pregnancies.
Tuesday, March 1, 2016The chromosome condition of DNA retrieved by blastocentesis was highly concordant with that found in trophectoderm cells, polar bodies, and blastomeres. Segmental abnormalities could also be detected in blastocoelic fluids.
Does the addition of time lapse morphokinetics in the selection of embryos for transfer improve pregnancy rates A randomized controlled trial
Monday, February 1, 2016This randomized controlled trial could not detect a statistically significant difference in reproductive outcomes when continuous time-lapse morphokinetic data was added to conventional screening criteria for embryo selection.
Noninferiority randomized controlled trial comparing embryo development using media developed for sequential or undisturbed culture in a time lapse setup
Monday, November 30, 2015In this randomized sibling study we found no differences in blastocyst development between sequential and single-step media.
Risk of preterm birth after blastocyst embryo transfer A large population study using contemporary registry data from Australia and New Zealand
Tuesday, September 29, 2015A large assisted reproductive technology registry study finds that blastocyst transfer does not increase the risk of preterm birth, low birth weight, or small for gestational age.
Antimullerian hormone as a predictor of good-quality supernumerary blastocyst cryopreservation among women with levels <1 ng mL versus 1 4 ng mL
Tuesday, September 1, 2015Antimullerian hormone (AMH) levels <1 ng/mL are associated with a statistically significantly lower likelihood of supernumerary good-quality blastocyst cryopreservation as compared with AMH levels between 1 and 4 ng/mL.
New strategy for diagnosing embryo implantation potential by combining proteomics and time lapse technologies
Wednesday, June 24, 2015We developed a diagnostic tool using a combination of proteomic fingerprinting and time-lapse morphokinetic analysis to select embryos for transfer according to their implantation potential.
Predictive value of maternal serum human chorionic gonadotropin levels in pregnancies achieved by in vitro fertilization with single cleavage and single blastocyst embryo transfers
Monday, June 1, 2015Mean human chorionic gonadotropin levels resulting from a single fresh blastocyst transfer were significantly higher than those from a single cleavage transfer after adjusting for confounding variables.
Deoxyribonucleic acid methylation profiling of single human blastocysts by methylated CpG island amplification coupled with CpG island microarray
Monday, June 1, 2015Methylated CpG-island amplification coupled with CpG-island microarray was used to assess DNA methylation in individual in vitro–derived human blastocysts, revealing 121 CpG islands that were hypermethylated in all 5 embryos.
Frozen thawed day 5 blastocyst transfer is associated with a lower risk of ectopic pregnancy than day 3 transfer and fresh transfer
Friday, February 27, 2015Frozen-thawed day 5 blastocyst transfer is associated with a lower ectopic pregnancy rate than frozen- thawed day 3 transfer and fresh transfer in patients undergoing IVF-ET.
In vitro development of donated frozen thawed human embryos in a prototype static microfluidic device A randomized controlled trial
Friday, February 27, 2015This study shows that a microfluidic device tested under static conditions supports single-embryo culture of donated frozen-thawed human day-4 embryos to advanced blastocyst stages.
Friday, January 30, 2015
Blastocysts with a more developed inner cell mass developed into newborns with a greater weight, when corrected for gestational age and gender.…