C Jun NH2 terminal Kinase JNK inhibitor Bentamapimod reduces induced endometriosis in baboons An assessor blind placebo controlled randomized study

Tuesday, March 1, 2016
We discuss how c-Jun NH2-terminal kinase inhibition reduces endometriosis without hormonal suppression.

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Nuclear magnetic resonance metabolomic profiling of urine provides a noninvasive alternative to the identification of biomarkers associated with endometriosis

Thursday, October 29, 2015
A comparative analysis of urine metabolomic profiles, based on 1H-NMR spectroscopy, of endometriosis patients and healthy women facilitates the noninvasive identification of metabolites discriminating both groups.

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Biomarkers of exposure to molybdenum and other metals in relation to testosterone among men from the United States National Health and Nutrition Examination Survey 2011 2012

Monday, December 29, 2014
Molybdenum and several other metals were associated with altered testosterone in men, which may have important implications as altered testosterone has been linked to many adverse health effects.

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New tools for enhancing collaborative endometriosis research

Thursday, July 10, 2014
Four articles present consensus of two international workshops from the World Endometriosis Research Foundation regarding standardization of phenotyping, sample collection, and biobanking to facilitate collaborative endometriosis research.

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MicroRNAs Key gene expression regulators

Sunday, June 1, 2014
Review of the basic principles of miRNA biology, including miRNA biogenesis, mechanisms of action, detection methods, functional effects, and possibilities as biomarkers and as pharmacologic agents in human reproduction.

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Potential biomarkers of nonobstructive azoospermia identified in microarray gene expression analysis

Wednesday, November 27, 2013
The potential biomarkers of azoospermia and molecular indicators that could determine particular stages of impaired spermatogenesis can be identified with GeneChip Human Gene 1.0 ST arrays.

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Biomarkers of chemotherapy induced testicular damage

Thursday, October 31, 2013
Chemotherapy treatment in men negatively impacts the male reproductive tract, and damage can potentially be transmitted to subsequent generations. Sensitive molecular biomarkers of injury are needed to ensure recovery of reproductive health.

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Differential seminal plasma proteome according to semen retrieval in men with spinal cord injury

Monday, September 30, 2013
Spinal cord injury is responsible for alterations in the seminal protein profile, leading to enrichment of a number of different gene ontology functions that may account for decreased fertility.

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Proteomics of the human endometrium and uterine fluid A pathway to biomarker discovery

Monday, March 18, 2013
Uterine fluid provides the microenvironment for blastocyst hatching and early implantation; it is easily sampled and relatively free of cellular proteins, enabling effective proteomic analyses for markers of endometrial receptivity.

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Biomarkers of ovarian response Current and future applications

Monday, March 18, 2013
Assessment of current strengths and limitations of antimullerian hormone and antral follicle count as ovarian biomarkers for assisted reproduction and evaluation of their future clinical applications by other health-care providers.

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Cumulus and granulosa cell markers of oocyte and embryo quality

Monday, March 18, 2013
Retrospective cohort studies correlated changes in cumulus/granulosa cell gene expression with embryo competence. A clinical benefit from the use of identified biomarker genes remains to be demonstrated in randomized trials.

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Preface Biomarkers

Monday, March 18, 2013
This Biomarkers in Reproductive Medicine special issue has been produced with the aim of providing a comprehensive view of the state of the art, and future, of reproductive medicine.

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The role and challenges of biomarkers in spontaneous preterm birth and preeclampsia

Monday, March 18, 2013
Despite the promise of biologically plausible biomarkers to identify patients at increased risk for spontaneous preterm birth and/or preeclampsia, the use of biomarkers in clinical practice to predict adverse obstetrical outcome remains challenging.

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Cell free fetal DNA and maternal serum analytes for monitoring embryonic and fetal status

Monday, March 18, 2013
Analyzing cell-free DNA in maternal serum analytes is currently the preferable noninvasive method for detecting fetal trisomy and many other abnormalities.

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Biomarkers in uterine leiomyoma

Monday, March 18, 2013
The biomarkers, biologic compounds that are easily accessible and reflect normal physiology or pathology, studied in uterine leiomyomas are currently not clinically useful.

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Differential metabolic profiling of non pure trisomy 21 human preimplantation embryos

Thursday, November 1, 2012
We aim to investigate the metabolomic signature of trisomy 21 human embryos, suggesting that differential metabolomic markers found in spent media could be used for chromosomal embryo selection.

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