Potential role of circulating microRNAs as a biomarker for unexplained recurrent spontaneous abortion

Sunday, May 1, 2016
Four circulating miRNAs (miR-320b, miR-146b-5p, miR-221-3p, miR-559) were up-regulated and one miRNA (miR-101-3p) was down-regulaed in unexplained recurrent spontaneous abortion (URSA). These circulating microRNAs may be involved in URSA pathogenesis and provide a promising new diagnostic biomarker for URSA.

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Serum microRNAs as diagnostic markers of endometriosis A comprehensive array based analysis

Tuesday, April 12, 2016

Authors:
Emine Cosar, M.D., Ramanaiah Mamillapalli, Ph.D., Gulcin Sahin Ersoy, M.D., SihYun Cho, M.D., Benjamin Seifer, B.S., Hugh S.…

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Assessing brain derived neurotrophic factor as a novel clinical marker of endometriosis

Tuesday, December 29, 2015
We discuss how brain-derived neurotrophic factor is a better predictor of endometriosis than nerve growth factor, neurotrophin 4/5, cancer antigen 125, and C-reactive protein in a cohort of 138 women.

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Follicular fluid and mural granulosa cells microRNA profiles vary in in vitro fertilization patients depending on their age and oocyte maturation stage

Tuesday, September 29, 2015
We describe the differential microRNA profiles in the follicular fluid and granulosa cells of in vitro fertilization patients depending on their age and oocyte maturation stage.

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Circulating miR 200 family microRNAs have altered plasma levels in patients with endometriosis and vary with blood collection time

Tuesday, September 29, 2015
Altered levels of circulating miR-200a and miR-141 but not miR-200b were observed in plasma samples of women with endometriosis. The levels of the miRNAs studied were influenced by the circadian rhythm.

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Pregnancy associated microRNAs in plasma as potential molecular markers of ectopic pregnancy

Wednesday, April 29, 2015
MicroRNAs with cell-free pregnancy have potential as molecular markers for ectopic pregnancy diagnosis.

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Circulating microRNAs as potential biomarkers for endometriosis

Wednesday, April 29, 2015
Several miRNAs are differentially expressed in sera of patients with endometriosis compared with controls; a combination of circulating miRNAs during the proliferative phase yielded high diagnostic performance in discriminating endometriosis.

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Noninvasive embryo viability assessment by quantitation of human haptoglobin alpha 1 fragment in the in vitro fertilization culture medium An additional tool to increase success rate

Friday, February 27, 2015
The measurement of the haptoglobin a-1 fragment in human serum albumin–supplemented culture medium serves as an alternative to assess viability by the exclusion of embryos having low implantation potential.

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Biomarkers of endometriosis

Monday, March 18, 2013
Prospective standardized biobank-based validation studies are needed for noninvasive diagnosis of endometriosis in symptomatic patients with pain and/or subfertility based on promising protein/peptide/micro-RNA (miRNA) biomarkers in peripheral blood and endometrium.

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The use of genomics proteomics and metabolomics in identifying biomarkers of male infertility

Monday, March 18, 2013
Biomarkers hold the keys to accurate diagnosis and treatment of male factor infertility. Their discovery is critical in eliminating invasive testing in the infertile male while developing novel targets for treatment.

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Biomarkers identified with time lapse imaging Discovery validation and practical application

Monday, March 18, 2013
Time-lapse markers that are supported by basic research, validated through prospective clinical studies, and accompanied by a reliable quantification technology may improve embryo selection and IVF success.

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Biomarkers for ectopic pregnancy and pregnancy of unknown location

Monday, March 18, 2013
Novel biomarkers for ectopic pregnancy and/or pregnancy of unknown location could have clinical utility, but none are currently validated. A biomarker test will likely be made of multiple markers and may include newly discovered markers.

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Biomarkers in reproductive medicine The promise and can it be fulfilled

Monday, March 18, 2013
Biomarkers have great potential in many areas of reproductive medicine, but few have realized their potential.

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A platform for evaluating sperm RNA biomarkers: dysplasia of the fibrous sheath—testing the concept

Friday, May 4, 2012
Correlative transcript pairs have suggested their potential use as biomarkers for male fertility. The results show that qPCR may provide a low-cost assay to assess dysplasia of the fibrous sheath.

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