Increased risk of incident chronic medical conditions in infertile men Analysis of United States claims data

Tuesday, March 1, 2016
Men diagnosed with male factor infertility had a significantly higher risk of adverse health outcomes in the years after an infertility evaluation.

Read More

Predictors of spermatogenesis in radical orchiectomy specimen and potential implications for patients with testicular cancer

Wednesday, February 24, 2016

Authors:
Ohad Shoshany, M.D., Yariv Shtabholtz, M.D., Eran Schreter, M.D., Maxim Yakimov, M.D., Haim Pinkas, M.D., Anat Stein, Ph.D., Jack Baniel, M.D., Shay Golan, M.D.…

Read More

Risks beyond reproduction for infertile men

Monday, February 1, 2016

Author:
Michael L. Eisenberg, M.D.…

Read More

Experimental methods to preserve male fertility and treat male factor infertility

Monday, February 1, 2016
This article describes experimental stem cell and gene therapies that might be used to treat male factor infertility.

Read More

Fertility and Sterility 50 years ago today

Tuesday, December 29, 2015

Author:
Martin Kathrins, M.D.…

Read More

The conversation

Thursday, October 29, 2015
This article provides a summary of the biopsychosocial model and the assessment and treatment of psychologically based male sexual dysfunction as manifested in cases of infertility.

Read More

Diagnostic evaluation of the infertile male A committee opinion

Friday, February 27, 2015

Authors:
Practice Committee of the American Society for Reproductive Medicine

Volume 103, Issue 3, Page e18

Abstract:

The purpose of this ASRM Practice Committee report is to provide clinicians with principles and strategies for the evaluation of couples with male infertility problems.…

Read More

Copy number variation associated with meiotic arrest in idiopathic male infertility

Monday, December 29, 2014
In an assessment of the presence of copy number variations (CNV) in men presenting with meiosis arrest and azoospermia, we detected two unique CNVs and several in known meiosis genes.

Read More

Genomic and genetic variation in E2F transcription factor 1 in men with nonobstructive azoospermia

Monday, December 29, 2014
E2F1 gene dosage changes were identified in 7.3% of nonobstructive azoospermic men but rarely occur in the general population, suggesting a role for E2F1 in male fertility.

Read More

Levels of liver x receptors in testicular biopsies of patients with azoospermia

Wednesday, July 30, 2014
This study shows differences in mRNA levels of the transcription factors LXRs and some of their downstream genes in testes of men with nonobstructive azoospermia and obstructive azoospermia.

Read More

Microdissection testicular sperm extraction in men with Sertoli cell only testicular histology

Wednesday, July 23, 2014
Diagnostic testis biopsy in nonobstructive azoospermia has little value, even when uniform Sertoli cell–only pattern is seen. When both testis volume and follicle-stimulating hormone are considered, sperm retrieval rates are 7%–45%.

Read More

Decreased expression of SAM68 in human testes with spermatogenic defects

Wednesday, June 25, 2014
Deficient expression of SAM68 might be one of the factors involved in the mechanism underlying spermatogenic defects. These results may offer new perspectives on the molecular basis of abnormal spermatogenesis.

Read More

Cystic fibrosis transmembrane regulator mutation and congenital bilateral absence of the vas deferens A bad combination for successful intracytoplasmic sperm injection outcomes

Wednesday, April 30, 2014
Reflections on "Association of cystic fibrosis transmembrane-conductance regulator gene mutation with negative outcome of intracytoplasmic sperm injection pregnancy in cases of congenital bilateral absence of vas deferens" by Lu et al.

Read More

Operating characteristics of follicle stimulating hormone in azoospermic men

Wednesday, April 30, 2014
In a retrospective cohort study of azoospermic patients, the full operating characteristics of follicle stimulating hormone were determined to allow for proper education of patients and individualized treatment based on specific risk.

Read More

Delineating the association between isodicentric chromosome Y and infertility A retrospective study

Monday, March 31, 2014
Exploring the association between male infertility and idic (Yq) chromosome using cytogenetic techniques on blood and semen germ cells could help in genetic counseling and choosing the proper reproduction technique.

Read More

Potential biomarkers of nonobstructive azoospermia identified in microarray gene expression analysis

Wednesday, November 27, 2013
The potential biomarkers of azoospermia and molecular indicators that could determine particular stages of impaired spermatogenesis can be identified with GeneChip Human Gene 1.0 ST arrays.

Read More

Cysteine rich secretory protein 1 in seminal plasma potential biomarker for the distinction between obstructive and nonobstructive azoospermia

Thursday, October 31, 2013
Seminal CRISP1 was measured to distinguish between obstructive and nonobstructive azoospermia. The receiver operating characteristic plots demonstrated a high diagnostic accuracy for CRISP1 to diagnose the cause of azoospermia.

Read More

Fertilization and embryo development with spermatozoa obtained from testicular sperm extraction into oocytes generated from human chorionic gonadotropin primed in vitro maturation cycles

Monday, September 30, 2013
The fertilization rate and embryo development of IVM oocytes after intracytoplasmic sperm injection (ICSI) using testicular spermatozoa was lower than that of sibling in vivo-matured oocytes.

Read More

Outcome of ICSI cycles with fresh testicular spermatozoa obtained on the day of or the day before oocyte collection and with cryopreserved testicular sperm in patients with azoospermia

Monday, September 30, 2013
Fresh testicular spermatozoa obtained at different time periods before oocyte retrieval and those cryopreserved yield similar pregnancy rates in ICSI cycles.

Read More

Increased risk of cancer among azoospermic men

Friday, August 30, 2013
Men with azoospermia have an increased risk of subsequently developing cancer, suggesting a possible common etiology between azoospermia and cancer development.

Read More

The relevance of increased cancer risk in infertile men

Friday, August 30, 2013
Reflections on "Increased risk of cancer among azoospermic men" by Eisenberg et al.

Read More

Perspectives on repeat sperm retrieval in nonobstructive azoospermia

Friday, June 28, 2013
Reflections on "Evaluation of diagnostic testis biopsy and the repetition of testicular sperm extraction surgeries in infertility patients" by Hussein et al.

Read More

Intracytoplasmic sperm injection with microsurgically retrieved spermatozoa in azoospermic men infected with human immunodeficiency virus 1 or hepatitis C virus The EP43 AZONECO ANRS study

Friday, March 1, 2013
Density gradient and washing can remove HCV RNA or HIV RNA from microsurgical epididymal sperm aspiration or testicular sperm extraction samples obtained from HCV- or HIV-infected azoospermic men before ICSI.

Read More

Overweight men with nonobstructive azoospermia have worse pregnancy outcomes after microdissection testicular sperm extraction

Monday, February 4, 2013
Overweight men have lower clinical pregnancy rate after microdissection testicular sperm extraction and intracytoplasmic sperm injection compared with men with normal weight. Men with body mass index >43 kg/m2 did not contribute to any pregnancies despite successful sperm retrieval.

Read More

Size does matter Higher body mass index may mean lower pregnancy rates for microscopic testicular sperm extraction

Monday, February 4, 2013
Reflections on "Overweight men with nonobstructive azoospermia have worse pregnancy outcomes following microdissection testicular sperm extraction" by Ramasamy et al.

Read More

Application of a ready to use calcium ionophore increases rates of fertilization and pregnancy in severe male factor infertility

Thursday, November 29, 2012
Patients with severe male factor infertility treated with a ready-to-use ionophore achieve high fertilization and pregnancy rates.

Read More

ETV5 mutations Revisiting Sertoli cell-only syndrome

Thursday, September 27, 2012
Reflections on "Genetic variants in the ETV5 gene in fertile and infertile men with nonobstructive azoospermia associated with Sertoli cell–only syndrome"

Read More

Supersensitive fluorescent semen analysis: Validation on azoospermic and oligozoospermic samples

Thursday, September 27, 2012
The improved sensitivity of a fluorescent-based semen analysis technique indicates that a substantial proportion of patients diagnosed as azoospermic by conventional semen analysis may actually have sperm present in their ejaculate.

Read More

Quadruplex real-time polymerase chain reaction assay for molecular diagnosis of Y-chromosomal microdeletions

Thursday, May 10, 2012
The diagnostic method for Y-chromosomal microdeletions in the European Academy of Andrology/European Molecular Genetics Quality Network guidelines has been successfully upgraded to a quadruplex realtime polymerase chain reaction assay that can be readily applied as clinical routine.

Read More

AZFb microdeletions and oligozoospermia—which mechanisms?

Thursday, May 10, 2012
Atypical deletion patterns are presented in two oligozoospermic males. The Y chromosome with highly repetitive block sequences in AZFb and AZFc led to deletions by intrachromosomal recombination mechanisms (28w).

Read More

Translate »