Economics of assisted reproductive technology data from an international analysis

Tuesday, December 31, 2013
Reflections on "The impact of consumer affordability on access to assisted reproductive technologies and embryo transfer practices: an international analysis" by Chambers et al.

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Risk and safety management in infertility and assisted reproductive technology

Wednesday, November 27, 2013
A review of various aspects of risk and safety management in ART.

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Could safety boards provide a valuable tool to enhance the safety of reproductive medicine

Wednesday, November 27, 2013
The National Transportation Safety Board provides an excellent model for a safety program that could enhance safety in the practice of all aspects of reproductive medicine.

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The national epidemic of multiple pregnancy and the contribution of assisted reproductive technology

Monday, September 30, 2013
Multiple pregnancy remains the most common complication of ART. The incidence of high-order multiple (HOM) pregnancies (triplets and greater) increased fivefold within 18 years and the total number peaked a decade ago. The incidence of twins and HOMs remains high but the proportion due to ART is much less than previously suspected, and the relative contribution of other factors greater.

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Endometrial signaling pathways during ovarian stimulation for assisted reproduction technology

Friday, August 30, 2013
Endometrial hormone receptor expression was altered during ovarian stimulation cycles and was independent from serum E2 levels.

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Risk sharing or refund programs in assisted reproduction a committee opinion

Wednesday, July 31, 2013
This opinion of the ASRM Ethics Committee analyzes the ethical issues raised by assisted reproduction program fee structures in which patients pay more initially but receive a partial refund if treatment fails.

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The assisted reproduction technology laboratory toward evidence based practice

Wednesday, July 31, 2013
In the human assisted reproduction laboratory, should equipment, utensils, and consumables, as well as culture and embryo selection strategies, be systematically evaluated before being introduced into routine use?

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Effect of maternal chronic disease on obstetric complications in twin pregnancies in a United States cohort

Friday, June 28, 2013
Among twin pregnancies, maternal chronic disease was associated with additional risk of earlier delivery and cesarean section after spontaneous labor, but not with other obstetric complications.

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Why we may abandon basal follicle stimulating hormone testing A sea change in determining ovarian reserve using antimüllerian hormone

Friday, May 31, 2013
Antimullerian hormone is a more informative and therefore a better serum test of ovarian reserve than basal FSH.

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Trophectoderm grade predicts outcomes of single blastocyst transfers

Thursday, March 28, 2013
Trophectoderm grading, but not inner cell mass grading, significantly correlates with implantation and live birth for single-embryo transfers.

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Treatment discontinuation in couples consulting for male infertility after failing to conceive

Thursday, March 28, 2013
Of the 1,345 couples who consulted for male factor infertility, 407 patients discontinued treatment principally due to painfulness of treatment and its ineffectiveness. Of these patients, 20% finally succeeded in having a child.

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Embryology in the era of proteomics

Monday, March 18, 2013
A review of the contribution of proteomic technologies in the identification of the human embryonic secretome.

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Effects of pregnancy planning fertility and Assisted Reproductive Treatment on child behavioral problems at 5 and 7 years Evidence from the Millennium Cohort Study

Monday, February 4, 2013
Children conceived by ART had higher mean total difficulties scores than planned, naturally conceived children, yet scores mostly remained within the “normal” range, and there was no significant increase in clinically relevant behavioral problems.

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Cardiometabolic health of children conceived by assisted reproductive technologies

Monday, February 4, 2013
Despite remaining data gaps, findings do not support that children conceived by ART differ in growth compared with non-ART children, although a signal of increased blood pressure warrants further investigation.

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Assisted Reproductive Technologies and Perinatal Morbidity Interrogating the Association

Monday, February 4, 2013
Despite lack of the perfect study, the perinatal consequences of ART are apparent while investigation into long-term clinical outcome is needed and continues.

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Diagnosis and Treatment of Diminished Ovarian Reserve in assisted reproductive technology Cycles of Women Up to Age 40 Years The Role of Insurance Mandates

Monday, February 4, 2013
DOR (up to age 40) is more prevalent in ART cycles performed in states lacking mandated ART coverage than in states with coverage. Mandates may impact outcomes in DOR cycles.

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Congenital anomalies after assisted reproductive technology

Monday, February 4, 2013
The adjusted risk of congenital anomalies in assisted reproductive technology versus spontaneously conceived children is only slightly increased, and it seems that malformation rates are declining over time.

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Endometrin as Luteal Phase Support in Assisted Reproduction

Wednesday, January 2, 2013
Endometrin monotherapy provided comparable pregnancy rates (PRs) in fresh autologous and fresh donor oocyte cycles. The addition of P in oil to endometrin improved PRs in frozen transfer cycles.

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Predicting fertility with antimullerian hormone Is a cutoff value adequate

Thursday, November 29, 2012
Reflections on "Low concentration of circulating antimüllerian hormone is not predictive of reduced fecundability in young healthy women: a prospective cohort study" by Hagen et al.

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Mens body mass index in relation to embryo quality and clinical outcomes in couples undergoing in vitro fertilization

Thursday, November 1, 2012
Men’s body mass index was not associated with clinical outcomes among couples undergoing conventional IVF, but male obesity was related to lower odds of live birth after intracytoplasmic sperm injection.

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Venous thromboembolism in relation to in vitro fertilization: an approach to determining the incidence and increase in risk in successful cycles

Friday, June 1, 2012
The incidence of first-trimester venous thromboembolism in IVF pregnancies was 0.2%, which was mainly attributed to a 100-fold increased risk in cycles complicated by ovarian hyperstimulation syndrome.

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Pretreatment with estrogen does not affect IVF-ICSI cycle outcome compared with no pretreatment in GnRH antagonist protocol: a prospective randomized trial

Wednesday, May 30, 2012
GnRH antagonist protocols allow friendly IVF procedures for patients but have low convenience to program oocyte retrievals. This study shows that estrogen pretreatment is effective and safe to program antagonist cycles.

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Development and current applications of assisted fertilization

Thursday, May 24, 2012
We describe the early steps that brought forth the development of intracytoplasmic sperm injection and its role in assisted reproduction techniques.

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Is cryopreservation of embryos a legitimate surrogate marker of embryo quality in studies of assisted reproductive technology conducted using national databases?

Thursday, May 10, 2012
We report on how having embryos frozen is associated with good quality embryos but not having embryos frozen is not a marker of poor embryo quality.

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November 2011 Featured Author Interview Video: Growth Hormone for Poor Responders in ART

Saturday, May 5, 2012

Author Interview  – Drs. 

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Recurrent IVF failure: other factors

Friday, May 4, 2012
Beyond embryo and endometrium, other known and suspected causes of recurrent IVF failure include obesity, uterine anomalies and fibroids, thyroid disease, tobacco smoke, immune factors, and thrombophilias.

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